Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10186794 | 0.92 | PDE4A (0.44) | PDE4APDE4B | |
| SCHEMBL10186745 | 0.90 | PDE4A (0.54) | PDE4APDE4B | |
| SCHEMBL10186806 | 0.84 | PDE4B (0.42) | PDE4APDE4B | |
| SCHEMBL10186805 | 0.81 | PDE4A (0.30) | PDE4APDE4B | |
| SCHEMBL10186679 | 0.80 | PDE4B (0.45) | PDE4APDE4B | |
| SCHEMBL10186807 | 0.78 | PDE4B (0.42) | PDE4APDE4B | |
| SCHEMBL10186784 | 0.77 | PDE4A (0.33) | PDE4APDE4B | |
| SCHEMBL10186822 | 0.77 | PDE4A (0.34) | PDE4APDE4B | |
| SCHEMBL10186789 | 0.77 | PDE4A (0.31) | PDE4APDE4B | |
| SCHEMBL10186727 | 0.76 | PDE4B (0.53) | PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120035132-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2012-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120035132-A1 | BORON-CONTAINING SMALL MOLECULES | BTD, BCL6B, BBOX1 | PDE4A 1744/4885PDE4B 936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.