⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8249419 | 0.74 | — | — | |
| SCHEMBL18176099 | 0.74 | — | — | |
| SCHEMBL84838 | 0.74 | — | — | |
| SCHEMBL2838629 | 0.74 | — | — | |
| SCHEMBL18116846 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL16465149 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL28954973 | 0.72 | — | — | |
| SCHEMBL5929452 | 0.70 | — | — | |
| SCHEMBL1256322 | 0.70 | — | — | |
| SCHEMBL19993250 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119524129-A | Monoamine oxidase inhibitors as modulators of beta cell vulnerability in type 1 diabetes | 乔斯林糖尿病中心 | 2025-02-28 | — | — | CN | claimed |
| CN-105636438-A | Pharmaceutical composition comprising an AMPK activator and a serotonin active agent and uses thereof | CHEN JIANHONG | 2016-06-01 | — | — | CN | claimed |
| CN-119524129-A | Monoamine oxidase inhibitors as modulators of beta cell vulnerability in type 1 diabetes | 乔斯林糖尿病中心 | 2025-02-28 | — | — | CN | disclosed |
| CN-117693516-A | Crystalline forms of neuroactive steroid | 萨奇治疗股份有限公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-117561264-A | 3H,4H,5H,6H, 7H-pyrimido [4,5-b ] [1,4] oxazine-4, 6-dione derivatives as TRPA1 inhibitors | 勃林格殷格翰国际有限公司 | 2024-02-13 | — | — | CN | disclosed |
| CN-117545758-A | Imidazo [4,5-d ] pyridazinone derivatives as TRPA1 inhibitors | 勃林格殷格翰国际有限公司 | 2024-02-09 | — | — | CN | disclosed |
| CN-117295731-A | Prodrugs of PDE10 compounds | 默沙东有限责任公司 | 2023-12-26 | — | — | CN | disclosed |
| CN-117222652-A | 3H, 4H-thieno [2,3-d ] pyrimidin-4-one derivatives as TRPA1 inhibitors | 勃林格殷格翰国际有限公司 | 2023-12-12 | — | — | CN | disclosed |
| CN-117083269-A | Uracil derivatives as TRPA1 inhibitors | 勃林格殷格翰国际有限公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-116981450-A | Combination of antidepressants and dextromethorphan for the treatment of neuropsychiatric disorders | 安泰赛普生物风投二代有限责任公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-110540497-B | Method for preparing oxalic acid by using yellow phosphorus tail gas | 雷波凯瑞磷化工有限责任公司 | 2021-06-04 | — | — | CN | disclosed |
| CN-105636438-A | Pharmaceutical composition comprising an AMPK activator and a serotonin active agent and uses thereof | CHEN JIANHONG | 2016-06-01 | — | — | CN | disclosed |
| WO-2014056771-A1 | NEW PYRROLIDINE DERIVATIVES AND THEIR USE AS ACETYL-COA CARBOXYLASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-04-17 | — | — | WO | disclosed |
| CN-102753019-A | Compounds for the treatment of neurological disorders | NEUROP INC | 2012-10-24 | — | — | CN | disclosed |
| WO-2012001107-A1 | PIPERIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-01-05 | — | — | WO | disclosed |
| CN-100441182-C | Nociceptin compounds | EURO CELTIQUE SA (LU) | 2008-12-10 | — | — | CN | disclosed |
| CN-1568188-A | Nociceptin analogs | EURO CELTIQUE SA (LU) | 2005-01-19 | — | — | CN | disclosed |
| CN-1561211-A | Nociceptin analogs | EURO CELTIQUE SA (LU) | 2005-01-05 | — | — | CN | disclosed |
| CN-1516584-A | Spiropyrazole compounds | ŷ�����ǹɷ�����˾ | 2004-07-28 | — | — | CN | disclosed |
| US-3936444-A | FROM A LACTIM-ETHER AND AN ARYL OR HETEROARYL HYDRAZINE, ACID CATALYST | BAYER AKTIENGESELLSCHAFT (DT) | 1976-02-03 | — | — | US | disclosed |