Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 13/20 | 0.56 |
| ▸ | FEN1 | P39748 | 12/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15915710 | 0.80 | ALOX5AP (0.51) | ALOX5APFEN1MEN1KMT2ASCN9A | |
| SCHEMBL28669539 | 0.80 | ALOX5AP (0.51) | ALOX5APFEN1MEN1KMT2ASCN9A | |
| SCHEMBL6406892 | 0.78 | MAPT (0.50) | ALOX5APFEN1MEN1KMT2AMAPT | |
| SCHEMBL1456723 | 0.75 | SCN9A (0.67) | ALOX5APFEN1MEN1KMT2ASCN9A | |
| SCHEMBL22534746 | 0.74 | MEN1 (0.65) | ALOX5APFEN1MEN1KMT2AMAP4K4 | |
| SCHEMBL15916764 | 0.73 | ALOX5AP (1.00) | ALOX5APFEN1 | |
| SCHEMBL24155500 | 0.73 | ALOX5AP (0.46) | ALOX5APFEN1MEN1KMT2A | |
| SCHEMBL15916144 | 0.72 | ALOX5AP (1.00) | ALOX5APFEN1 | |
| SCHEMBL30073089 | 0.70 | KDM4E (0.53) | MEN1KMT2AMAP4K4MAPTKDM4E | |
| SCHEMBL27930554 | 0.70 | KDM4E (0.53) | MEN1KMT2AMAP4K4MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012001107-A1 | PIPERIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-01-05 | — | — | WO | disclosed |