Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | FURIN | P09958 | 2/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12260856 | 0.98 | PARP10 (0.47) | PARP10ALDH1A1TSHRHPGDFURIN | |
| SCHEMBL470127 | 0.91 | HRH1 (0.43) | PARP10ALDH1A1TSHRFURINHRH3 | |
| SCHEMBL2242868 | 0.85 | PARP10 (0.55) | PARP10ALDH1A1TSHRHPGDFURIN | |
| SCHEMBL18620969 | 0.81 | HRH1 (0.66) | HRH3HRH1 | |
| SCHEMBL747626 | 0.79 | PARP10 (0.55) | PARP10ALDH1A1TSHRHPGDFURIN | |
| SCHEMBL623629 | 0.77 | PARP10 (0.53) | PARP10ALDH1A1TSHRHPGDFURIN | |
| SCHEMBL1837838 | 0.77 | PARP10 (0.53) | PARP10ALDH1A1TSHRHPGDFURIN | |
| SCHEMBL9304772 | 0.77 | SLC6A4 (0.58) | PARP10ALDH1A1TSHRHPGDFURIN | |
| SCHEMBL7541489 | 0.77 | PARP10 (0.48) | PARP10ALDH1A1TSHRHPGDFURIN | |
| SCHEMBL8171032 | 0.77 | EGFR (0.49) | PARP10ALDH1A1TSHRHPGDFURIN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012001107-A1 | PIPERIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-01-05 | — | — | WO | disclosed |