Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 2/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.37 |
| ▸ | AKT1 | P31749 | 4/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 3/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 5/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23024963 | 0.80 | BTK (0.36) | SMPD3BTKAKT1RIPK1RPS6KB1 | |
| SCHEMBL26975070 | 0.79 | AKT1 (0.38) | BTKHRH4AKT1RIPK1RPS6KB1 | |
| SCHEMBL792633 | 0.79 | EGLN2 (0.40) | BTKAKT1RIPK1RPS6KB1DPP4 | |
| SCHEMBL6119348 | 0.79 | AKT1 (0.38) | BTKAKT1RIPK1RPS6KB1DPP4 | |
| SCHEMBL19004851 | 0.76 | AKT1 (0.47) | BTKHRH4AKT1RIPK1DPP4 | |
| SCHEMBL807296 | 0.76 | SMN1; SMN2 (0.50) | BTKHRH4AKT1DPP4 | |
| SCHEMBL30579439 | 0.76 | SMN1; SMN2 (0.50) | BTKHRH4AKT1DPP4 | |
| SCHEMBL19004850 | 0.75 | MAP4K4 (0.42) | BTKAKT1RIPK1RPS6KB1DPP4 | |
| SCHEMBL10187281 | 0.75 | LRRK2 (0.42) | AKT1DPP4 | |
| SCHEMBL12650637 | 0.75 | HRH3 (0.51) | BTKHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012001107-A1 | PIPERIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-01-05 | — | — | WO | disclosed |