Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.81 |
| ▸ | RAB9A | P51151 | 6/20 | 0.71 |
| ▸ | NPC1 | O15118 | 4/20 | 0.71 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.66 |
| ▸ | EGFR | P00533 | 5/20 | 0.58 |
| ▸ | CDK1 | P06493 | 1/20 | 0.56 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.56 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.56 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.56 |
| ▸ | CDK2 | P24941 | 1/20 | 0.56 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.56 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | ERBB3 | P21860 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1097149 | 0.98 | MEN1 (0.78) | MEN1KMT2ARAB9ANPC1SCN9A | |
| SCHEMBL12485614 | 0.83 | MEN1 (0.87) | MEN1KMT2ARAB9ANPC1EGFR | |
| SCHEMBL856014 | 0.82 | MEN1 (0.78) | MEN1KMT2ARAB9ANPC1SCN9A | |
| SCHEMBL4109259 | 0.81 | MEN1 (0.66) | MEN1KMT2ARAB9ANPC1NR4A1 | |
| SCHEMBL3182550 | 0.81 | MEN1 (0.66) | MEN1KMT2ARAB9ANPC1SCN9A | |
| SCHEMBL13064955 | 0.81 | CDK5 (0.61) | MEN1KMT2ARAB9ANPC1SCN9A | |
| SCHEMBL30046349 | 0.81 | SCN9A (0.76) | MEN1KMT2ARAB9ANPC1SCN9A | |
| SCHEMBL12486513 | 0.80 | MEN1 (0.79) | MEN1KMT2ARAB9ANPC1EGFR | |
| SCHEMBL374428 | 0.80 | MEN1 (0.51) | MEN1KMT2ARAB9ANPC1SCN9A | |
| SCHEMBL13834481 | 0.80 | MEN1 (0.79) | MEN1KMT2ARAB9ANPC1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012001107-A1 | PIPERIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-01-05 | — | — | WO | disclosed |