Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.87 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.87 |
| ▸ | RAB9A | P51151 | 5/20 | 0.77 |
| ▸ | NPC1 | O15118 | 4/20 | 0.77 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.60 |
| ▸ | EGFR | P00533 | 8/20 | 0.59 |
| ▸ | ERBB3 | P21860 | 7/20 | 0.59 |
| ▸ | CDK4 | P11802 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10187337 | 0.83 | MEN1 (0.81) | MEN1KMT2ARAB9ANPC1TNNI3K | |
| SCHEMBL13570421 | 0.83 | MEN1 (0.79) | MEN1KMT2ARAB9ANPC1TNNI3K | |
| SCHEMBL12486513 | 0.83 | MEN1 (0.79) | MEN1KMT2ARAB9ANPC1TNNI3K | |
| SCHEMBL13834481 | 0.83 | MEN1 (0.79) | MEN1KMT2ARAB9ANPC1TNNI3K | |
| SCHEMBL856014 | 0.82 | MEN1 (0.78) | MEN1KMT2ARAB9ANPC1TNNI3K | |
| SCHEMBL1097149 | 0.82 | MEN1 (0.78) | MEN1KMT2ARAB9ANPC1TNNI3K | |
| SCHEMBL27339283 | 0.80 | MEN1 (0.74) | MEN1KMT2ARAB9ANPC1TNNI3K | |
| SCHEMBL12487662 | 0.80 | MEN1 (0.74) | MEN1KMT2ARAB9ANPC1TNNI3K | |
| SCHEMBL373960 | 0.79 | EGFR (0.57) | MEN1KMT2ARAB9ANPC1TNNI3K | |
| SCHEMBL2175110 | 0.79 | MEN1 (0.72) | MEN1KMT2ARAB9ANPC1TNNI3K |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2519501-B1 | SUBSTITUTED PYRIDINES AND PYRIMIDINES FOR THE PRODUCTION OF CARDIOMYOCYTE-LIKE CELLS | UNIV WIEN TECH (AT) | 2015-04-22 | — | — | EP | disclosed |
| US-8986994-B2 | Substituted pyridines and pyrimidines | TECHNISCHE UNIVERSITAET WIEN (AT) | 2015-03-24 | — | — | US | disclosed |
| US-8986994-B2 | Substituted pyridines and pyrimidines | TECHNISCHE UNIVERSITAET WIEN (AT) | 2015-03-24 | — | — | US | disclosed |
| US-20120294835-A1 | SUBSTITUTED PYRIDINES AND PYRIMIDINES | MEDIZINISCHE UNIVERSITAET WIEN (AT) | 2012-11-22 | — | — | US | disclosed |
| US-20120294835-A1 | SUBSTITUTED PYRIDINES AND PYRIMIDINES | MEDIZINISCHE UNIVERSITAET WIEN (AT) | 2012-11-22 | — | — | US | disclosed |
| WO-2011079343-A2 | SUBSTITUTED PYRIDINES AND PYRIMIDINES | TECHNISCHE UNIVERSITAET WIEN (AT) | 2011-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120294835-A1 | SUBSTITUTED PYRIDINES AND PYRIMIDINES | TNNI3, TNNT2, PROX1 | MEN1 4740/4885KMT2A 2502/4885RAB9A 2086/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.