Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | SRC | P12931 | 1/20 | 0.53 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.52 |
| ▸ | CLK1 | P49759 | 2/20 | 0.51 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29836749 | 0.84 | SRC (0.58) | FYNUSP2MAPTKMT2ASRC | |
| SCHEMBL3557764 | 0.80 | ADORA1 (0.51) | FYNUSP2MAPTKMT2ASRC | |
| SCHEMBL10165327 | 0.79 | ALDH1A1 (0.53) | USP2MAPTKMT2ASRCCHEK2 | |
| SCHEMBL18270880 | 0.78 | CHEK2 (0.61) | FYNUSP2MAPTKMT2ASRC | |
| SCHEMBL1702288 | 0.78 | FYN (0.45) | FYNUSP2MAPTKMT2ACHEK2 | |
| SCHEMBL12137775 | 0.77 | ADORA2A (0.47) | FYNUSP2MAPTKMT2ASRC | |
| SCHEMBL3901839 | 0.76 | CA12 (0.61) | USP2MAPTKMT2ASRCADORA2A | |
| SCHEMBL16331696 | 0.76 | FYN (1.00) | FYNUSP2MAPTKMT2ACHEK1 | |
| SCHEMBL22684994 | 0.76 | MAPT (0.50) | FYNUSP2MAPTKMT2ASRC | |
| SCHEMBL28843776 | 0.76 | TAAR1 (0.50) | FYNMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012001107-A1 | PIPERIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-01-05 | — | — | WO | disclosed |