SCHEMBL101878

SCHEMBL101878

[CH2]CC(C)CCCCCCCCCCCCCC

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ACE2 Q9BYF1 1/20 0.48
OPRM1 P35372 1/20 0.46
SPHK1 Q9NYA1 1/20 0.43
LMNA P02545 1/20 0.42
TSHR P16473 1/20 0.42
THRB P10828 1/20 0.42
DNM1 Q05193 2/20 0.42
ADH1B P00325 1/20 0.40
ADH1C P00326 1/20 0.40
ADH1A P07327 1/20 0.40
ADH4 P08319 1/20 0.40
ADH7 P40394 1/20 0.40
GPR84 Q9NQS5 3/20 0.38
FDPS P14324 3/20 0.38
FFAR1 O14842 1/20 0.38
CA1 P00915 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL102497 1.00 ACE2 (0.48) ACE2OPRM1SPHK1LMNATSHR
SCHEMBL103308 1.00 ACE2 (0.48) ACE2OPRM1SPHK1LMNATSHR
SCHEMBL201001 1.00 ACE2 (0.48) ACE2OPRM1SPHK1LMNATSHR
SCHEMBL199750 1.00 ACE2 (0.48) ACE2OPRM1SPHK1LMNATSHR
SCHEMBL102914 1.00 ACE2 (0.48) ACE2OPRM1SPHK1LMNATSHR
SCHEMBL7888892 1.00 ACE2 (0.48) ACE2OPRM1SPHK1LMNATSHR
SCHEMBL7939027 1.00 ACE2 (0.48) ACE2OPRM1SPHK1LMNATSHR
SCHEMBL101629 1.00 ACE2 (0.48) ACE2OPRM1SPHK1LMNATSHR
SCHEMBL103793 1.00 ACE2 (0.48) ACE2OPRM1SPHK1LMNATSHR
SCHEMBL199645 1.00 ACE2 (0.48) ACE2OPRM1SPHK1LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118201905-A Cationic lipid 武田药品工业株式会社 2024-06-14 CN disclosed
WO-2024018761-A1 NEUTRAL LIPID AND LIPID NANOPARTICLE 国立大学法人北海道大学 2024-01-25 WO disclosed
WO-2024018762-A1 PH-SENSITIVE CATIONIC LIPID AND LIPID NANOPARTICLE 国立大学法人北海道大学 2024-01-25 WO disclosed
WO-2023085299-A1 CATIONIC LIPID 武田薬品工業株式会社 2023-05-19 WO disclosed
US-10800895-B2 Polymer slides having hydrophobic small molecules STRATEC CONSUMABLES GmbH (AT) 2020-10-13 US disclosed
CN-109761854-B Synthetic method of hydroximic acid compound 中南大学 2020-07-14 CN disclosed
CN-109761837-B Preparation method and application of amido carboxylic acid compounds 中南大学 2020-05-15 CN disclosed
US-10611890-B2 Method of producing a polymer part and polymer part STRATEC CONSUMABLES GmbH (AT) 2020-04-07 US disclosed
CN-109761854-A The synthetic method of hydroximic acid compound 中南大学 2019-05-17 CN disclosed
CN-109761837-A The preparation method and application of amido-carboxylic acid class compound 中南大学 2019-05-17 CN disclosed
US-20130131188-A1 Cosmetic Preparations COGNIS IP MANAGEMENT GMBH (DE) 2013-05-23 US disclosed
CN-103068786-A Cosmetic preparation COGNIS IP MAN GMBH 2013-04-24 CN disclosed
EP-2426101-A1 Cosmetic preparations Cognis IP Management GmbH (DE) 2012-03-07 EP disclosed
WO-2012016642-A1 COSMETIC PREPARATIONS COGNIS IP MANAGEMENT GMBH (DE) 2012-02-09 WO disclosed
CN-101426879-A Viscosity index improving agent and lubricating oil composition SANYO CHEMICAL IND LTD (JP) 2009-05-06 CN disclosed
EP-2009074-A1 VISCOSITY INDEX IMPROVER AND LUBRICANT COMPOSITION Sanyo Chemical Industries, Ltd. (JP) 2008-12-31 EP disclosed
US-20070270521-A1 Transition metal compound, polymerization-initiator system comprising the same, and process for producing polymer SUMITOMO CHEMICAL COMPANY, LIMITED 2007-11-22 US disclosed
CN-101024659-A Transition metal compound, polymerization initiator system including same and polymer production method SUMITOMO CHEMICAL CO (JP) 2007-08-29 CN disclosed
US-6833421-B1 Compound ROLIC AG (CH) 2004-12-21 US disclosed
US-4229467-A Alkoxy benzofuran carboxylic acids and salts and esters thereof as hypolipidemic agents RICHARDSON-MERRELL INC. (US) 1980-10-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130131188-A1 Cosmetic Preparations CYP1B1, CBR1, ACOX3 ACE2 3825/4885OPRM1 745/4885SPHK1 1590/4885
US-20070270521-A1 Transition metal compound, polymerization-initiator system comprising the same, and process for producing polymer CARM1, CPN1, CCNT1 ACE2 710/4885OPRM1 290/4885SPHK1 3958/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.