Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAG1 | P54619 | 14/20 | 0.56 |
| ▸ | PRKAB1 | Q9Y478 | 14/20 | 0.56 |
| ▸ | PRKAA2 | P54646 | 10/20 | 0.56 |
| ▸ | PRKAA1 | Q13131 | 9/20 | 0.56 |
| ▸ | PRKAB2 | O43741 | 3/20 | 0.56 |
| ▸ | PRKAG3 | Q9UGI9 | 3/20 | 0.56 |
| ▸ | PRKAG2 | Q9UGJ0 | 3/20 | 0.56 |
| ▸ | TFDP2 | Q14188 | 1/20 | 0.56 |
| ▸ | AMY1A | P0DUB6 | 4/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3163783 | 0.90 | PRKAG1 (0.68) | PRKAG1PRKAB1PRKAA2PRKAA1PRKAB2 | |
| Ammonia Solution, Strong SCHEMBL3481236 | 0.90 | PRKAG1 (0.67) | PRKAG1PRKAB1PRKAA2PRKAA1PRKAB2 | |
| Ammonia Solution, Strong SCHEMBL3481233 | 0.90 | PRKAG1 (0.67) | PRKAG1PRKAB1PRKAA2PRKAA1PRKAB2 | |
| Trifluoroacetic Acid SCHEMBL3481217 | 0.86 | PRKAG1 (0.63) | PRKAG1PRKAB1PRKAA2PRKAA1PRKAB2 | |
| SCHEMBL13437535 | 0.83 | PRKAG1 (0.63) | PRKAG1PRKAB1PRKAA2PRKAA1PRKAB2 | |
| SCHEMBL13437480 | 0.82 | PRKAG1 (0.69) | PRKAG1PRKAB1PRKAA2PRKAA1PRKAB2 | |
| SCHEMBL10112842 | 0.82 | PRKAG1 (0.58) | PRKAG1PRKAB1PRKAA2PRKAA1PRKAB2 | |
| SCHEMBL13385186 | 0.81 | PRKAG1 (0.83) | PRKAG1PRKAB1PRKAA2PRKAA1PRKAB2 | |
| SCHEMBL13437441 | 0.80 | PRKAG1 (0.72) | PRKAG1PRKAB1PRKAA2PRKAA1PRKAB2 | |
| SCHEMBL6996298 | 0.79 | PRKAG1 (0.76) | PRKAG1PRKAB1PRKAA2PRKAA1PRKAB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012044567-A2 | IMIDAZOLE DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2012-04-05 | — | — | WO | disclosed |