SCHEMBL10189840

SCHEMBL10189840

Cc1nnc(N)n1-c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
AVPR1A P37288 1/20 0.56
SMN1; SMN2 Q16637 3/20 0.49
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
GAA P10253 1/20 0.47
KDM4E B2RXH2 1/20 0.45
ALDH1A1 P00352 2/20 0.45
MAPK1 P28482 2/20 0.44
HTT P42858 1/20 0.44
TSHR P16473 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2C19 P33261 1/20 0.44
PI4KA P42356 1/20 0.44
PI4K2B Q8TCG2 1/20 0.44
PI4K2A Q9BTU6 1/20 0.44
PI4KB Q9UBF8 1/20 0.44
OXTR P30559 1/20 0.42
EGFR P00533 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3421771 0.84 AVPR1A (0.67) AVPR1AMEN1KMT2AKDM4EALDH1A1
SCHEMBL16870657 0.78 AVPR1A (0.59) AVPR1ASMN1; SMN2MEN1KMT2AGAA
SCHEMBL9069362 0.75 AVPR1A (0.56) AVPR1ASMN1; SMN2MEN1KMT2AGAA
SCHEMBL19068734 0.75 AVPR1A (0.56) AVPR1ASMN1; SMN2MEN1KMT2AGAA
SCHEMBL544662 0.75 SMN1; SMN2 (0.49) AVPR1ASMN1; SMN2MEN1KMT2AGAA
SCHEMBL515383 0.75 AVPR1A (0.92) AVPR1ASMN1; SMN2MEN1KMT2AKDM4E
SCHEMBL9299272 0.75 AVPR1A (0.56) AVPR1ASMN1; SMN2MEN1KMT2AKDM4E
SCHEMBL1562739 0.75 AVPR1A (0.56) AVPR1ASMN1; SMN2MEN1KMT2AGAA
SCHEMBL17153776 0.73 KDM4E (0.59) AVPR1ASMN1; SMN2MEN1KMT2AGAA
SCHEMBL29406171 0.73 AVPR1A (0.89) AVPR1ASMN1; SMN2MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190189932-A1 TRANSPARENT ELECTRODE AND ELECTRONIC DEVICE Konica Minolta, Inc. (JP) 2019-06-20 US disclosed
EP-2083819-B1 PDE10 INHIBITORS AND RELATED COMPOSITIONS AND METHODS OMEROS CORP (US) 2017-02-22 EP disclosed
US-8093400-B2 Compounds useful in therapy PFIZER INC. (US) 2012-01-10 US disclosed
US-20100317652-A1 Compounds Useful In Therapy PFIZER INC 2010-12-16 US disclosed
US-7745630-B2 Triazolyl piperidine arginine vasopressin receptor modulators BRYANS JUSTIN STEPHEN 2010-06-29 US disclosed
US-7741017-B2 Silver halide color photographic light-sensitive material and image formation method using the same, silver halide emulsion, reducing compound having group adsorptive to silver halide and method for producing the same FUJIFILM CORPORATION (JP) 2010-06-22 US disclosed
US-20080242860-A1 SILVER HALIDE COLOR PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL AND IMAGE FORMATION METHOD USING THE SAME, SILVER HALIDE EMULSION, REDUCING COMPOUND HAVING GROUP ADSORPTIVE TO SILVER HALIDE AND METHOD FOR PRODUCING THE SAME FUJIFILM CORPORATION (JP) 2008-10-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080242860-A1 SILVER HALIDE COLOR PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL AND IMAGE FORMATION METHOD USING THE SAME, SILVER HALIDE EMULSION, REDUCING COMPOUND HAVING GROUP ADSORPTIVE TO SILVER HALIDE AND METHOD FOR PRODUCING THE SAME IK, APOL1, CLTA AVPR1A 4449/4885SMN1; SMN2 3915/4885MEN1 4369/4885
US-20100317652-A1 Compounds Useful In Therapy AVPR1A, AVPR1B, AVPR2 AVPR1A 1/4885SMN1; SMN2 4519/4885MEN1 1081/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.