SCHEMBL10189971

SCHEMBL10189971

CN(C)c1cc[n+](Cc2ccc(C(=O)Oc3ccc(C(=O)Oc4ccc(C(=O)O)cc4)cc3)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ CHKA P35790 10/20 0.54
▸ ALDH1A1 P00352 4/20 0.51
▸ LMNA P02545 2/20 0.51
▸ HTT P42858 2/20 0.51
▸ SMN1; SMN2 Q16637 2/20 0.51
▸ ATM Q13315 1/20 0.47
▸ RXRA P19793 1/20 0.44
▸ RXRB P28702 1/20 0.44
▸ MAPT P10636 1/20 0.42
▸ HPGD P15428 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13475880 0.90 CHKA (0.54) CHKAALDH1A1LMNAHTTSMN1; SMN2
SCHEMBL13475993 0.90 CHKA (0.54) CHKAALDH1A1LMNAHTTSMN1; SMN2
SCHEMBL22924917 0.90 CHKA (0.54) CHKAALDH1A1LMNAHTTSMN1; SMN2
SCHEMBL27119654 0.90 CHKA (0.54) CHKAALDH1A1LMNAHTTSMN1; SMN2
SCHEMBL24597567 0.90 CHKA (0.54) CHKAALDH1A1LMNAHTTSMN1; SMN2
SCHEMBL24597615 0.87 CHKA (0.53) CHKAALDH1A1LMNAHTTSMN1; SMN2
SCHEMBL13475884 0.84 CHKA (0.59) CHKAALDH1A1LMNAHTTSMN1; SMN2
SCHEMBL13930852 0.83 CHKA (0.59) CHKALMNASMN1; SMN2MAPT
SCHEMBL13475883 0.83 CHKA (0.59) CHKALMNASMN1; SMN2MAPT
SCHEMBL13475877 0.83 CHKA (0.59) CHKALMNASMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8153246-B2 Optical compensatory film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-04-10 — — US disclosed
US-7876403-B2 Optical compensation film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2011-01-25 — — US disclosed
US-7658864-B2 Liquid crystal composition, optical compensation film and liquid crystal display device FUJIFILM CORPORATION (JP) 2010-02-09 — — US disclosed
US-20090273740-A1 OPTICAL COMPENSATORY FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2009-11-05 — — US disclosed
US-20090180059-A1 OPTICAL COMPENSATION FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2009-07-16 — — US disclosed
US-20090040435-A1 LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2009-02-12 — — US disclosed
US-20090009693-A1 Liquid Crystal Composition, Optical Compensation Film and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2009-01-08 — — US disclosed
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