Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 3/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 11/20 | 0.41 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL97732 | 0.91 | PIK3CA (0.53) | PIK3CAHDAC1PIK3CDPIK3R1PDE10A | |
| SCHEMBL99717 | 0.91 | PIK3CA (0.48) | PIK3CAHDAC1PIK3CDPIK3R1PDE10A | |
| SCHEMBL98759 | 0.88 | PIK3CA (0.51) | PIK3CAHDAC1PIK3CDPIK3R1PDE10A | |
| SCHEMBL101086 | 0.87 | PIK3CA (0.50) | PIK3CAHDAC1PIK3CDPIK3R1PDE10A | |
| SCHEMBL98579 | 0.87 | PIK3CA (0.50) | PIK3CAHDAC1PIK3CDPIK3R1PDE10A | |
| SCHEMBL98240 | 0.87 | PIK3CA (0.50) | PIK3CAHDAC1PIK3CDPIK3R1PDE10A | |
| SCHEMBL99732 | 0.87 | PIK3CA (0.49) | PIK3CAHDAC1PIK3CDPIK3R1PDE10A | |
| SCHEMBL98635 | 0.86 | ALDH1A1 (0.52) | PIK3CAHDAC1PIK3CDPIK3R1PDE10A | |
| SCHEMBL98710 | 0.86 | PIK3CA (0.48) | PIK3CAHDAC1PIK3CDPIK3R1PDE10A | |
| SCHEMBL101395 | 0.85 | PIK3CA (0.50) | PIK3CAHDAC1PIK3CDPIK3R1PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120088765-A1 | PURINE DERIVATIVE AND ANTITUMOR AGENT USING SAME | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 2012-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120088765-A1 | PURINE DERIVATIVE AND ANTITUMOR AGENT USING SAME | PNP, TYMP, DPYD | PIK3CA 1539/4885HDAC1 3179/4885PIK3CD 2513/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.