SCHEMBL1019275

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1019801	0.89	TSHR (0.51)	TSHRGAATP53FLT3HSD17B10
	SCHEMBL1020983	0.89	TSHR (0.48)	TSHRGAATP53FLT3HSD17B10
	SCHEMBL1019620	0.86	FLT3 (0.43)	TSHRGAAFLT3LIG1KDM4E
	SCHEMBL15721585	0.85	TSHR (0.48)	TSHRGAATP53FLT3HSD17B10
	SCHEMBL8168167	0.82	TSHR (0.68)	TSHRGAATP53FLT3HSD17B10
	Hydrochloric Acid SCHEMBL8164468	0.81	TSHR (0.66)	TSHRGAATP53FLT3HSD17B10
	SCHEMBL1019663	0.80	FLT3 (0.40)	TSHRGAAFLT3LIG1KDM4E
	SCHEMBL4383790	0.79	TSHR (0.56)	TSHRGAATP53FLT3HSD17B10
	SCHEMBL4567029	0.79	PTPN11 (0.50)	TSHRTP53HSD17B10RXRASMN1; SMN2
	SCHEMBL31425472	0.79	P2RX3 (0.41)	TSHRHSD17B10KDM4EP2RX3P2RX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.