SCHEMBL10194253

SCHEMBL10194253

Cc1nsc(N=Nc2c(C)nn(-c3nc(-n4nc(C)c(N=Nc5nc(C)ns5)c4N)[nH]c(=O)n3)c2N)n1

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.33
MAPT P10636 2/20 0.33
RAB9A P51151 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
MEN1 O00255 1/20 0.33
MAPK1 P28482 1/20 0.33
KMT2A Q03164 1/20 0.33
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10194252 0.86 MAPT (0.35) NPC1MAPTRAB9ASMN1; SMN2TDP1
SCHEMBL10194275 0.81 MAPT (0.38) NPC1MAPTRAB9ASMN1; SMN2TDP1
SCHEMBL10194258 0.79 MAPT (0.36) NPC1MAPTRAB9ASMN1; SMN2TDP1
SCHEMBL824556 0.79 MAPT (0.36) NPC1MAPTRAB9ASMN1; SMN2TDP1
SCHEMBL10194282 0.78 MAPT (0.36) NPC1MAPTRAB9ASMN1; SMN2TDP1
SCHEMBL10194277 0.78 MAPT (0.36) NPC1MAPTRAB9ASMN1; SMN2TDP1
SCHEMBL824604 0.77 MAPT (0.36) NPC1MAPTRAB9ASMN1; SMN2TDP1
SCHEMBL824565 0.77 MAPT (0.41) NPC1MAPTRAB9ASMN1; SMN2TDP1
SCHEMBL824566 0.77 MAPT (0.36) NPC1MAPTRAB9ASMN1; SMN2TDP1
SCHEMBL10194280 0.76 MAPT (0.36) NPC1MAPTRAB9ASMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8118885-B2 Azo pigments, process for producing the azo pigments, and pigment dispersion, coloring composition and ink for inkjet recording containing the pigment FUJIFILM CORPORATION (JP) 2012-02-21 US disclosed
US-8118885-B2 Azo pigments, process for producing the azo pigments, and pigment dispersion, coloring composition and ink for inkjet recording containing the pigment FUJIFILM CORPORATION (JP) 2012-02-21 US disclosed
US-20110030583-A1 AZO PIGMENTS, PROCESS FOR PRODUCING THE AZO PIGMENTS, AND PIGMENT DISPERSION, COLORING COMPOSITION AND INK FOR INKJET RECORDING CONTAINING THE PIGMENT FUJIFILM COPORATION (JP) 2011-02-10 US disclosed
US-20110030583-A1 AZO PIGMENTS, PROCESS FOR PRODUCING THE AZO PIGMENTS, AND PIGMENT DISPERSION, COLORING COMPOSITION AND INK FOR INKJET RECORDING CONTAINING THE PIGMENT FUJIFILM COPORATION (JP) 2011-02-10 US disclosed
WO-2009005137-A2 AZO PIGMENTS, PROCESS FOR PRODUCING THE AZO PIGMENTS, AND PIGMENT DISPERSION, COLORING COMPOSITION AND INK FOR INKJET RECORDING CONTAINING THE PIGMENT FUJIFILM CORPORATION (JP) 2009-01-08 WO disclosed