SCHEMBL824604

SCHEMBL824604

Cc1nsc(/N=N/c2c(C)nn(-c3nc(=O)cc[nH]3)c2N)n1

nearest known ligand 0.36

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.36
RAB9A P51151 5/20 0.36
SMN1; SMN2 Q16637 5/20 0.36
TDP1 Q9NUW8 4/20 0.36
NPC1 O15118 4/20 0.36
MAPK1 P28482 3/20 0.36
KMT2A Q03164 3/20 0.36
MEN1 O00255 2/20 0.36
HPGD P15428 2/20 0.36
ALDH1A1 P00352 1/20 0.36
L3MBTL1 Q9Y468 2/20 0.33
HTT P42858 2/20 0.33
ALOX12 P18054 1/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL824607 0.83 MAPT (0.36) MAPTRAB9ASMN1; SMN2TDP1NPC1
SCHEMBL10194252 0.81 MAPT (0.35) MAPTRAB9ASMN1; SMN2TDP1NPC1
SCHEMBL824605 0.81 MAPT (0.34) MAPTRAB9ASMN1; SMN2TDP1NPC1
SCHEMBL824556 0.80 MAPT (0.36) MAPTRAB9ASMN1; SMN2TDP1NPC1
SCHEMBL824846 0.79 MAPT (0.35) MAPTRAB9ASMN1; SMN2TDP1NPC1
SCHEMBL10194253 0.77 NPC1 (0.33) MAPTRAB9ASMN1; SMN2TDP1NPC1
SCHEMBL10194285 0.77 MAPT (0.42) MAPTRAB9ASMN1; SMN2TDP1NPC1
SCHEMBL10194288 0.76 MAPT (0.44) MAPTRAB9ASMN1; SMN2TDP1NPC1
SCHEMBL824566 0.76 MAPT (0.36) MAPTRAB9ASMN1; SMN2TDP1NPC1
SCHEMBL10194287 0.75 MAPT (0.39) MAPTRAB9ASMN1; SMN2TDP1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8142519-B2 Azo pigment, and pigment dispersion, coloring composition and ink composition for inkjet recording containing the same FUJIFILM CORPORATION (JP) 2012-03-27 US disclosed
US-20100258036-A1 AZO PIGMENT, AND PIGMENT DISPERSION, COLORING COMPOSITION AND INK COMPOSITION FOR INKJET RECORDING CONTAINING THE SAME FUJIFILM CORPORATION (JP) 2010-10-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100258036-A1 AZO PIGMENT, AND PIGMENT DISPERSION, COLORING COMPOSITION AND INK COMPOSITION FOR INKJET RECORDING CONTAINING THE SAME WNT1, CYP1A1, CYP1B1 MAPT 372/4885RAB9A 910/4885SMN1; SMN2 3717/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.