SCHEMBL1019622

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1020114	0.90	HSP90AA1 (0.42)	HSP90AA1GAAADRB2ADRB1ADRB3
	SCHEMBL1019620	0.89	FLT3 (0.43)	GAAADRB2ADRB1ADRB3LIG1
	SCHEMBL1020983	0.86	TSHR (0.48)	HSP90AA1GAAADRB2ADRB1ADRB3
	SCHEMBL1019663	0.84	FLT3 (0.40)	GAAADRB2ADRB1ADRB3LIG1
	SCHEMBL3956309	0.82	KDM4E (0.49)	HSP90AA1GAALIG1CA12CA1
	SCHEMBL1022138	0.82	HSP90AA1 (0.42)	HSP90AA1GAACA12CA1CA2
	SCHEMBL3954124	0.82	GAA (0.44)	GAAADRB2ADRB1ADRB3LIG1
	SCHEMBL12765851	0.80	HSP90AA1 (0.40)	HSP90AA1GAACA12CA1CA2
	SCHEMBL1018553	0.80	HTT (0.47)	HSP90AA1GAACA12CA1CA2
	SCHEMBL1019801	0.78	TSHR (0.51)	HSP90AA1GAAADRB2ADRB1ADRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.