SCHEMBL1020114

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1019622	0.90	HSP90AA1 (0.40)	HSP90AA1FLT3CASP1ADRB2ADRB1
	SCHEMBL1019620	0.89	FLT3 (0.43)	FLT3CASP1ADRB2ADRB1ADRB3
	SCHEMBL1019801	0.86	TSHR (0.51)	HSP90AA1FLT3ADRB2ADRB1ADRB3
	SCHEMBL1019663	0.84	FLT3 (0.40)	FLT3CASP1ADRB2ADRB1ADRB3
	SCHEMBL1018764	0.82	HSP90AA1 (0.44)	HSP90AA1GAATSHRTDP1MAPT
	SCHEMBL20393894	0.81	FLT3 (0.50)	FLT3CASP1ADRB2ADRB1ADRB3
	SCHEMBL1018545	0.80	HTT (0.48)	HSP90AA1KDM4EBLMGAATSHR
	SCHEMBL20391495	0.79	TDP1 (0.49)	FLT3CASP1LIG1KDM4EBLM
	SCHEMBL1020983	0.78	TSHR (0.48)	HSP90AA1FLT3ADRB2ADRB1ADRB3
	SCHEMBL12765876	0.77	LMNA (0.41)	ADRB2ADRB1KDM4EGAATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.