Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | PPOX | P50336 | 1/20 | 0.42 |
| ▸ | MASP2 | O00187 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ESRRA | P11474 | 1/20 | 0.39 |
| ▸ | HPD | P32754 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16257077 | 0.86 | FFAR1 (0.40) | MAPTLMNAL3MBTL1 | |
| SCHEMBL10196193 | 0.85 | FFAR1 (0.45) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL10196237 | 0.85 | SLC6A4 (0.36) | MAPTCYP2C9LMNAL3MBTL1ESRRA | |
| SCHEMBL10196217 | 0.83 | CYP1A2 (0.44) | ALDH1A1MAPK1CYP2C9LMNAESRRA | |
| SCHEMBL10195597 | 0.81 | MAPT (0.43) | KDM4EALDH1A1MAPTHPGDMAPK1 | |
| SCHEMBL10196292 | 0.81 | MAPT (0.43) | KDM4EALDH1A1MAPTHPGDMAPK1 | |
| SCHEMBL10195344 | 0.80 | MAPT (0.43) | KDM4EALDH1A1MAPTHPGDMAPK1 | |
| SCHEMBL7176637 | 0.80 | ALDH1A1 (0.53) | KDM4EALDH1A1MAPTHPGDMAPK1 | |
| SCHEMBL10195555 | 0.79 | MAPT (0.41) | KDM4EALDH1A1MAPTHPGDMAPK1 | |
| SCHEMBL10196196 | 0.79 | MAPK1 (0.35) | ALDH1A1MAPTHPGDMAPK1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8895474-B2 | Herbicidally active cyclopentanediones and derivatives thereof, and their use in controlling weeds | SYNGENTA LIMITED (GB) | 2014-11-25 | — | — | US | disclosed |
| US-20120021912-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120021912-A1 | NOVEL HERBICIDES | DDT, CYP4X1, CYP1B1 | KDM4E 1092/4885ALDH1A1 14/4885MAPT 3903/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.