Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 6/20 | 0.56 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KLK7 | P49862 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tromethamine SCHEMBL1019735 | 0.89 | SERPINE1 (0.68) | SERPINE1CNR1MAPTKMT2AMEN1 | |
| SCHEMBL1015662 | 0.85 | SERPINE1 (0.64) | SERPINE1CNR1MAPTKMT2AMEN1 | |
| SCHEMBL1016107 | 0.84 | SERPINE1 (0.77) | SERPINE1CNR1MAPTKMT2AMEN1 | |
| SCHEMBL29492572 | 0.84 | SERPINE1 (0.77) | SERPINE1CNR1MAPTKMT2AMEN1 | |
| SCHEMBL22468222 | 0.83 | SERPINE1 (0.75) | SERPINE1CNR1MAPTKMT2AMEN1 | |
| SCHEMBL29448187 | 0.82 | SERPINE1 (0.64) | SERPINE1CNR1MAPTKMT2AMEN1 | |
| SCHEMBL20814654 | 0.79 | SERPINE1 (0.53) | SERPINE1CNR1MAPTKMT2AMEN1 | |
| SCHEMBL1016292 | 0.79 | SERPINE1 (0.61) | SERPINE1CNR1MAPTKMT2AMEN1 | |
| SCHEMBL1012933 | 0.77 | SERPINE1 (0.61) | SERPINE1CNR1MAPTKMT2AMEN1 | |
| SCHEMBL1012706 | 0.76 | SERPINE1 (0.80) | SERPINE1CNR1KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2272822-A1 | INHIBITOR OF PLASMINOGEN ACTIVATOR INHIBITOR-1 | Renascience CO., LTD. (JP) | 2011-01-12 | — | — | EP | disclosed |