Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 5/20 | 0.61 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | MGLL | Q99685 | 3/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1012706 | 0.86 | SERPINE1 (0.80) | SERPINE1CNR1MEN1POLBKMT2A | |
| SCHEMBL1015662 | 0.81 | SERPINE1 (0.64) | SERPINE1CNR1MAPTRAB9AMEN1 | |
| SCHEMBL1012933 | 0.81 | SERPINE1 (0.61) | SERPINE1CNR1MAPTRAB9AMEN1 | |
| SCHEMBL29492572 | 0.81 | SERPINE1 (0.77) | SERPINE1CNR1MAPTMEN1POLB | |
| SCHEMBL1016107 | 0.81 | SERPINE1 (0.77) | SERPINE1CNR1MAPTMEN1POLB | |
| SCHEMBL22468222 | 0.80 | SERPINE1 (0.75) | SERPINE1CNR1MAPTMEN1POLB | |
| SCHEMBL1014817 | 0.80 | SERPINE1 (0.76) | SERPINE1CNR1MEN1POLBKMT2A | |
| SCHEMBL1019736 | 0.79 | SERPINE1 (0.56) | SERPINE1CNR1MAPTMEN1POLB | |
| SCHEMBL418556 | 0.78 | SERPINE1 (0.61) | SERPINE1CNR1MEN1POLBKMT2A | |
| SCHEMBL1015090 | 0.78 | SERPINE1 (0.79) | SERPINE1CNR1MAPTRAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2272822-A1 | INHIBITOR OF PLASMINOGEN ACTIVATOR INHIBITOR-1 | Renascience CO., LTD. (JP) | 2011-01-12 | — | — | EP | disclosed |