SCHEMBL101977

SCHEMBL101977

N#Cc1cccc(Cl)c1Cl

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 1/20 0.47
TSHR P16473 2/20 0.42
GRIA1 P42261 1/20 0.40
CACNG8 Q8WXS5 1/20 0.40
TRPV4 Q9HBA0 1/20 0.40
PNMT P11086 1/20 0.39
HTR2A P28223 3/20 0.39
DRD2 P14416 2/20 0.39
CNR2 P34972 2/20 0.39
CNR1 P21554 1/20 0.39
P2RX7 Q99572 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2A6 P11509 1/20 0.38
HTR1A P08908 1/20 0.38
HTR7 P34969 1/20 0.38
PSMB8 P28062 3/20 0.37
KDM4E B2RXH2 3/20 0.37
ALDH1A1 P00352 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27895311 1.00 DYRK1A (0.47) DYRK1ATSHRGRIA1CACNG8TRPV4
SCHEMBL9480952 0.98 DYRK1A (0.46) DYRK1ATSHRGRIA1CACNG8TRPV4
Fluoride SCHEMBL27502055 0.98 DYRK1A (0.46) DYRK1ATSHRGRIA1CACNG8TRPV4
Hydroxyamine SCHEMBL28229541 0.91 DYRK1A (0.42) DYRK1ATSHRGRIA1CACNG8TRPV4
Bicarbonate SCHEMBL28187410 0.89 TSHR (0.48) DYRK1ATSHRGRIA1CACNG8KDM4E
SCHEMBL11099454 0.88 TSHR (0.52) DYRK1ATSHRGRIA1CACNG8HTR2A
SCHEMBL3237062 0.87 TSHR (0.46) DYRK1ATSHRTRPV4HTR2ACA1
Acetic Acid SCHEMBL28836539 0.86 TSHR (0.46) DYRK1ATSHRGRIA1CACNG8CYP1A2
SCHEMBL12017294 0.86 MAOA (0.48) DYRK1ATSHRCA2CYP2A6KDM4E
SCHEMBL28523518 0.85 KCNH2 (0.42) DYRK1ATSHRGRIA1CACNG8TRPV4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 997 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4743438-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF BENZONITRILE COMPOUNDS FROM THE BENZOTRICHLORIDE COMPOUNDS Aarti Industries Limited (IN) 2026-05-20 EP claimed
EP-4665705-A1 A PROCESSES FOR THE PREPARATION OF BENZONITRILE COMPOUNDS FROM THE CORRESPONDING BENZOTRICHLORIDE COMPOUNDS Aarti Industries Limited (IN) 2025-12-24 EP claimed
CN-120192521-A High molecular weight crystallization type polyarylether nitrile and preparation method thereof 电子科技大学 2025-06-24 CN claimed
WO-2025068995-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF BENZONITRILE COMPOUNDS FROM THE BENZOTRICHLORIDE COMPOUNDS AARTI INDUSTRIES LIMITED (IN) 2025-04-03 WO claimed
CN-119640588-A Preparation method of flexible protective layer for lithium metal negative electrode protection 四川成科国重新能源有限公司 2025-03-18 CN claimed
CN-119529267-A Production process of high-purity poly (arylene ether nitrile) 江苏维尤纳特精细化工有限公司 2025-02-28 CN claimed
CN-118448811-B Heat-resistant lithium ion battery diaphragm and preparation method thereof 湖南博盛新能源技术有限公司 2024-10-18 CN claimed
EP-3650120-B1 FLUIDIZED-BED CATALYST APPLICABLE TO HALOARYLNITRILE PRODUCTION, AND PREPARATION AND APPLICATION THEREOF CHINA PETROLEUM & CHEM CORP (CN) 2024-09-18 EP claimed
WO-2024171098-A1 A PROCESSES FOR THE PREPARATION OF BENZONITRILE COMPOUNDS FROM THE CORRESPONDING BENZOTRICHLORIDE COMPOUNDS AARTI INDUSTRIES LIMITED (IN) 2024-08-22 WO claimed
CN-118448811-A Heat-resistant lithium ion battery diaphragm and preparation method thereof 湖南博盛新能源技术有限公司 2024-08-06 CN claimed
EP-0635486-B1 Process for the preparation of fluorobenzonitriles CLARIANT GMBH (DE) 1998-12-09 EP claimed
CN-1124745-A Polyaryl ether nitrile and producing process thereof UNIV SICHUAN UNITED (CN) 1996-06-19 CN claimed
US-5466859-A Process for preparing fluorobenzonitriles HOECHST AKTIENGESELLSCHAFT (DE) 1995-11-14 US claimed
EP-0441004-B1 Process for preparing aromatic nitriles ENICHEM SINTESI (IT) 1995-09-06 EP claimed
EP-0635486-A2 Process for the preparation of fluorobenzonitriles HOECHST AKTIENGESELLSCHAFT (DE) 1995-01-25 EP claimed
EP-0441004-A1 Process for preparing aromatic nitriles ENICHEM SYNTHESIS S.p.A. (IT) 1991-08-14 EP claimed
US-4977234-A Reacting dihalogenobenzonitrile with resorcinol and alkali metal salt in presence of solvent; laminated electrical/ electronic procuct; heat/solvent resistance IDEMITSU KOSAN COMPANY LIMITED (JP) 1990-12-11 US claimed
EP-0243000-B1 POLYCYANOARYL ETHER, METHOD FOR PREPARING THE SAME AND USES THEREOF IDEMITSU KOSAN COMPANY LIMITED (JP) 1990-10-03 EP claimed
EP-0273317-A1 Process for producing 2,6-dichlorobenzonitrile NITTO CHEMICAL INDUSTRY CO., LTD. (JP) 1988-07-06 EP claimed
EP-0243000-A1 Polycyanoaryl ether, method for preparing the same and uses thereof IDEMITSU KOSAN COMPANY LIMITED (JP) 1987-10-28 EP claimed