Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10198321 | 0.90 | MAPK1 (0.38) | MAPK1RORCSCN9ALMNACYP2C9 | |
| SCHEMBL364199 | 0.80 | SCN9A (0.41) | MAPK1RORCSCN9ALMNACYP2C9 | |
| SCHEMBL12391387 | 0.79 | RORC (0.39) | RORCTSHR | |
| SCHEMBL12391388 | 0.77 | P2RY12 (0.40) | MAPK1RORCSCN9ARAB9A | |
| SCHEMBL16175138 | 0.76 | MAPK1 (0.40) | MAPK1RORCSCN9ALMNACYP2C9 | |
| SCHEMBL16240182 | 0.75 | SCN9A (0.45) | MAPK1RORCSCN9ALMNACYP2C9 | |
| SCHEMBL365906 | 0.73 | MAPK1 (0.47) | MAPK1LMNACYP2C9TSHRAPEX1 | |
| SCHEMBL364997 | 0.73 | S1PR1 (0.41) | MAPK1RORCSCN9ALMNACYP2C9 | |
| SCHEMBL365394 | 0.73 | S1PR1 (0.41) | MAPK1RORCSCN9ALMNACYP2C9 | |
| SCHEMBL10198424 | 0.73 | S1PR1 (0.41) | MAPK1RORCSCN9ALMNACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130109708-A1 | Chemical Compounds | PFIZER LIMITED (GB) | 2013-05-02 | — | — | US | disclosed |
| US-20120010183-A1 | Chemical Compounds | PFIZER LIMITED (GB) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130109708-A1 | Chemical Compounds | SCN1A, SCN1B, SCN7A | MAPK1 222/4885RORC 3411/4885SCN9A 20/4885 |
| US-20120010183-A1 | Chemical Compounds | SCN1A, SCN1B, SCN7A | MAPK1 147/4885RORC 2944/4885SCN9A 25/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.