Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.31 |
| ▸ | KDR | P35968 | 3/20 | 0.31 |
| ▸ | GSK3A | P49840 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10198341 | 0.92 | AAK1 (0.42) | AAK1ALPLPDGFRBKDRGSK3A | |
| SCHEMBL365161 | 0.84 | AAK1 (0.44) | AAK1ALPLPDGFRBKDRGSK3A | |
| SCHEMBL16175121 | 0.83 | AAK1 (0.46) | AAK1ALPLPDGFRBKDRGSK3A | |
| SCHEMBL367669 | 0.82 | AAK1 (0.43) | AAK1ALPLPDGFRBKDRGSK3A | |
| SCHEMBL16175226 | 0.80 | AAK1 (0.43) | AAK1ALPLPDGFRBKDRGSK3A | |
| SCHEMBL29556254 | 0.79 | ALPL (0.45) | AAK1ALPLPDGFRBKDRGSK3A | |
| SCHEMBL3673238 | 0.79 | ALPL (0.45) | AAK1ALPLPDGFRBKDRGSK3A | |
| SCHEMBL364697 | 0.79 | AAK1 (0.47) | AAK1ALPLPDGFRBKDRGSK3A | |
| SCHEMBL1690230 | 0.79 | AAK1 (0.47) | AAK1ALPLPDGFRBKDRGSK3A | |
| SCHEMBL10198423 | 0.79 | AAK1 (0.47) | AAK1ALPLPDGFRBKDRGSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130109708-A1 | Chemical Compounds | PFIZER LIMITED (GB) | 2013-05-02 | — | — | US | disclosed |
| US-20120010183-A1 | Chemical Compounds | PFIZER LIMITED (GB) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130109708-A1 | Chemical Compounds | SCN1A, SCN1B, SCN7A | AAK1 3006/4885ALPL 4596/4885PDGFRB 4164/4885 |
| US-20120010183-A1 | Chemical Compounds | SCN1A, SCN1B, SCN7A | AAK1 1882/4885ALPL 4612/4885PDGFRB 4055/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.