Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 2/20 | 0.67 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.67 |
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL255190 | 0.80 | CHRM5 (1.00) | CHRM5CHRM3SIGMAR1NPC1POLB | |
| SCHEMBL11130645 | 0.79 | CHRM5 (0.62) | CHRM5CHRM3SIGMAR1ALDH1A1KMT2A | |
| SCHEMBL1023592 | 0.78 | CHRM5 (0.57) | CHRM5CHRM3SIGMAR1NPC1POLB | |
| SCHEMBL3399852 | 0.76 | CHRM5 (0.57) | CHRM5CHRM3SIGMAR1ALDH1A1KMT2A | |
| SCHEMBL974224 | 0.75 | SIGMAR1 (0.61) | CHRM5CHRM3SIGMAR1NPC1GAA | |
| SCHEMBL12226505 | 0.73 | CHRM5 (0.53) | CHRM5CHRM3SIGMAR1GAAALDH1A1 | |
| SCHEMBL13381313 | 0.73 | CHRM5 (0.58) | CHRM5CHRM3SIGMAR1NPC1POLB | |
| SCHEMBL2915702 | 0.72 | CHRM5 (0.53) | CHRM5CHRM3SIGMAR1ALDH1A1KMT2A | |
| SCHEMBL983664 | 0.72 | CHRM5 (0.71) | CHRM5CHRM3SIGMAR1NPC1POLB | |
| SCHEMBL4711520 | 0.72 | SIGMAR1 (0.65) | CHRM5CHRM3SIGMAR1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011000945-A9 | AMINOALKAMIDES FOR USE IN THE TREATMENT OF INFLAMMATORY, DEGENERATIVE OR DEMYELINATING DISEASES OF THE CNS | NENSIUS RESEARCH A/S (DK) | 2011-04-07 | — | — | WO | disclosed |
| WO-2011000945-A2 | AMINOALKAMIDES FOR USE IN THE TREATMENT OF INFLAMMATORY, DEGENERATIVE OR DEMYELINATING DISEASES OF THE CNS | NENSIUS RESEARCH A/S (DK) | 2011-01-06 | — | — | WO | disclosed |