Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.57 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.55 |
| ▸ | PPARA | Q07869 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2822682 | 0.93 | PPARA (0.54) | PPARGPARP10PPARAKMT2AMEN1 | |
| SCHEMBL22209208 | 0.85 | PPARG (0.74) | PPARGPPARAKMT2AMEN1ALDH1A1 | |
| SCHEMBL19514689 | 0.81 | PPARA (0.74) | PPARGPPARARAB9AL3MBTL1MAPT | |
| SCHEMBL19514688 | 0.81 | PPARA (0.74) | PPARGPPARARAB9AL3MBTL1MAPT | |
| SCHEMBL3948925 | 0.79 | PPARA (0.47) | PPARGPARP10PPARAKMT2AMEN1 | |
| SCHEMBL4000649 | 0.79 | PPARA (0.47) | PPARGPARP10PPARAKMT2AMEN1 | |
| SCHEMBL11545612 | 0.79 | PPARA (0.71) | PPARGPPARAKMT2AMEN1ALDH1A1 | |
| SCHEMBL18260725 | 0.78 | PPARA (0.46) | PPARGPPARAKMT2AMEN1ALDH1A1 | |
| SCHEMBL3233909 | 0.78 | KMT2A (0.47) | PPARGPPARAKMT2AMEN1NPC1 | |
| SCHEMBL4688589 | 0.78 | PPARA (0.48) | PPARGPARP10PPARAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125735-B1 | 2,2,2-TRI-SUBSTITUTED ACETAMIDE DERIVATIVES AS GLUCOKINASE ACTIVATORS, THEIR PROCESS AND PHARMACEUTICAL APPLICATION | ADVINUS THERAPEUTICS PRIVATE LTD (IN) | 2012-06-27 | — | — | EP | disclosed |