Sugi Predict

Sugi Predict / Compounds / SCHEMBL2822682

SCHEMBL2822682

SCHEMBL2822682

CC(C)(Oc1ccccc1)C(N)=O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PPARA Q07869 12/20 0.54
▸ KMT2A Q03164 3/20 0.50
▸ MAPT P10636 2/20 0.50
▸ CYP2C19 P33261 2/20 0.48
▸ MEN1 O00255 2/20 0.48
▸ CYP1A2 P05177 1/20 0.48
▸ CYP3A4 P08684 1/20 0.48
▸ CYP2D6 P10635 1/20 0.48
▸ PPARG P37231 9/20 0.47
▸ PPARD Q03181 2/20 0.44
▸ CYP2C9 P11712 1/20 0.44
▸ HSD11B1 P28845 1/20 0.44
▸ HSD11B2 P80365 1/20 0.44
▸ KDM4E B2RXH2 1/20 0.42
▸ ALDH1A1 P00352 1/20 0.42
▸ POLB P06746 1/20 0.42
▸ TSHR P16473 1/20 0.42
▸ PARP10 Q53GL7 1/20 0.42
▸ FABP2 P12104 1/20 0.42
▸ SLC22A12 Q96S37 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10198566 0.93 PPARG (0.57) PPARAKMT2AMAPTCYP2C19MEN1
SCHEMBL19514688 0.84 PPARA (0.74) PPARAMAPTPPARGPPARD
SCHEMBL19514689 0.84 PPARA (0.74) PPARAMAPTPPARGPPARD
Methylamine SCHEMBL27865949 0.83 PPARA (0.63) PPARAKMT2AMAPTCYP2C19MEN1
SCHEMBL11279744 0.83 KMT2A (0.50) PPARAKMT2AMAPTCYP2C19MEN1
SCHEMBL247466 0.83 PPARA (0.68) PPARAKMT2AMAPTCYP2C19MEN1
SCHEMBL3948925 0.82 PPARA (0.47) PPARAKMT2AMAPTCYP2C19MEN1
SCHEMBL4000649 0.82 PPARA (0.47) PPARAKMT2AMAPTCYP2C19MEN1
SCHEMBL7032523 0.81 PPARA (0.66) PPARAKMT2AMAPTCYP2C19MEN1
Ammonia Solution, Strong SCHEMBL7026339 0.81 PPARA (0.66) PPARAKMT2AMAPTCYP2C19MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3987175-A ATHEROSCLEROSIS PIERRE FABRE S.A. (FR) 1976-10-19 — — US claimed
JP-63159369-A — — None — — JP disclosed
JP-61126071-A — — None — — JP disclosed
WO-2025019825-A2 SUBSTITUTED 2-(3,5-DICHLORO-4-(4-HYDROXY-BENZYL)PHENOXY)ACETAMIDE DERIVATIVES BRII BIOSCIENCES, INC. (US) 2025-01-23 — — WO disclosed
CN-116444420-A Small molecule inhibitor of beta-catenin/BCL 9 protein interaction and application thereof 上海医药工业研究院有限公司 2023-07-18 — — CN disclosed
CN-115697415-A Techniques for preventing or treating infections 拜尔哈文制药股份有限公司 2023-02-03 — — CN disclosed
US-20220380319-A1 SUBSTITUTED BENZIMIDAZOLE CARBOXAMIDES AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS BIAL R&D INVEST S A (PT) 2022-12-01 — — US disclosed
EP-4031532-A1 SUBSTITUTED BENZIMIDAZOLE CARBOXAMIDES AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS Bial-R&D Investments, S.A. (PT) 2022-07-27 — — EP disclosed
CN-114787136-A Substituted benzimidazole carboxamides and their use in the treatment of medical disorders 比亚尔R&D投资股份公司 2022-07-22 — — CN disclosed
WO-2022125862-A1 PROCESSES FOR THE PREPARATION OF ZANUBRUTINIB AND INTERMEDIATES THEREOF TEVA PHARMACEUTICALS INTERNATIONAL GMBH (CH) 2022-06-16 — — WO disclosed
EP-2797895-B1 FUNGICIDAL 3-[(1,3-THIAZOL-4-YLMETHOXYIMINO)(PHENYL)METHYL]-2-SUBSTITUTED-1,2,4-OXADIAZOL-5(2H)-ONE DERIVATIVES BAYER IP GMBH (DE) 2015-08-05 — — EP disclosed
US-20150031730-A1 FUNGICIDAL 3-[(1,3-THIAZOL-4-YLMETHOXYIMINO)(PHENYL)METHYL]-2-SUBSTITUTED-1,2,4-OXADIAZOL-5(2H)-ONE DERIVATIVES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2015-01-29 — — US disclosed
US-8507493-B2 Amide and amidine derivatives and uses thereof ABBVIE INC. (US) 2013-08-13 — — US disclosed
US-20120232120-A1 AMINO ACID AMIDES OF PHENOXYBUTYRIC ACID DERIVATIVES LALEZARI IRAJ (US) 2012-09-13 — — US disclosed
CN-102459158-A Novel amide and amidine derivatives and use thereof ABBOTT LAB 2012-05-16 — — CN disclosed
WO-2010123838-A2 NOVEL AMIDE AND AMIDINE DERIVATIVES AND USES THEREOF ABBOTT LABORATORIES (US) 2010-10-28 — — WO disclosed
EP-2243479-A2 Novel amide and amidine derivates and uses thereof Abbott Laboratories (US) 2010-10-27 — — EP disclosed
US-20100267738-A1 NOVEL AMIDE AND AMIDINE DERIVATIVES AND USES THEREOF ABBOTT LABORATORIES (US) 2010-10-21 — — US disclosed
JP-S63159369-A PHENOXYISOBUTYRAMIDE DERIVATIVE HOKKO CHEM IND CO LTD 1988-07-02 — — JP disclosed
JP-S61126071-A PHENOXYISOBUTYRIC ACID AMIDE DERIVATIVE, AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE HOKKO CHEM IND CO LTD 1986-06-13 — — JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100267738-A1 NOVEL AMIDE AND AMIDINE DERIVATIVES AND USES THEREOF HSD11B2, HSD11B1, HSD17B2 PPARA 650/4885KMT2A 2829/4885MAPT 4080/4885
US-20150031730-A1 FUNGICIDAL 3-[(1,3-THIAZOL-4-YLMETHOXYIMINO)(PHENYL)METHYL]-2-SUBSTITUTED-1,2,4-OXADIAZOL-5(2H)-ONE DERIVATIVES CYP51A1, TH, CYP4X1 PPARA 2051/4885KMT2A 1261/4885MAPT 2290/4885
US-20120232120-A1 AMINO ACID AMIDES OF PHENOXYBUTYRIC ACID DERIVATIVES SLC1A5, BCAT2, PAH PPARA 525/4885KMT2A 729/4885MAPT 1190/4885
US-20220380319-A1 SUBSTITUTED BENZIMIDAZOLE CARBOXAMIDES AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS GAA, GBA1, CLN6 PPARA 2091/4885KMT2A 254/4885MAPT 483/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.