Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.40 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 2/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL571118 | 0.89 | USP2 (0.46) | USP2SMN1; SMN2USP30SCD5CYP11B2 | |
| SCHEMBL349283 | 0.88 | USP2 (0.42) | USP2SMN1; SMN2USP30SCD5CYP11B2 | |
| SCHEMBL2520614 | 0.81 | USP2 (0.42) | USP2SMN1; SMN2USP30SCD5CYP11B2 | |
| SCHEMBL4298314 | 0.80 | USP2 (0.51) | USP2SMN1; SMN2HPGDTSHRALOX15 | |
| SCHEMBL22405855 | 0.79 | HPGD (0.44) | USP2SMN1; SMN2USP30SCD5CYP11B2 | |
| SCHEMBL29023689 | 0.78 | USP2 (0.49) | USP2SMN1; SMN2USP30SCD5CYP11B2 | |
| SCHEMBL13689493 | 0.78 | USP2 (0.49) | USP2SMN1; SMN2USP30HPGDTSHR | |
| SCHEMBL24672559 | 0.77 | USP2 (0.51) | USP2SMN1; SMN2HPGDTSHRALOX15 | |
| SCHEMBL2218646 | 0.77 | USP2 (0.47) | USP2SMN1; SMN2USP30SCD5CYP11B2 | |
| SCHEMBL25286793 | 0.77 | USP2 (0.47) | USP2SMN1; SMN2USP30SCD5CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011044538-A9 | ANTIBACTERIAL AMINOGLYCOSIDE ANALOGS | ACHAOGEN, INC. (US) | 2012-01-05 | — | — | WO | disclosed |
| WO-2011044538-A1 | ANTIBACTERIAL AMINOGLYCOSIDE ANALOGS | ACHAOGEN, INC. (US) | 2011-04-14 | — | — | WO | disclosed |