Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.45 |
| ▸ | CDC7 | O00311 | 13/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 9/20 | 0.36 |
| ▸ | CDK2 | P24941 | 9/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 9/20 | 0.36 |
| ▸ | DBF4 | Q9UBU7 | 9/20 | 0.36 |
| ▸ | PIM1 | P11309 | 4/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 4/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.35 |
| ▸ | CIT | O14578 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.35 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 3/20 | 0.34 |
| ▸ | TYMS | P04818 | 1/20 | 0.34 |
| ▸ | CCNC | P24863 | 2/20 | 0.33 |
| ▸ | CDK8 | P49336 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10201776 | 0.85 | SCN10A (0.53) | SCN10ACDC7CCNE1CDK2ROCK1 | |
| SCHEMBL14758479 | 0.82 | CDC7 (0.48) | SCN10ACDC7CCNE1CDK2ROCK1 | |
| SCHEMBL12373613 | 0.81 | TYMS (0.33) | TYMS | |
| SCHEMBL10236922 | 0.80 | SCN10A (0.38) | SCN10ACDC7CCNE1CDK2ROCK1 | |
| SCHEMBL19488489 | 0.80 | CDC7 (0.38) | SCN10ACDC7CCNE1CDK2ROCK1 | |
| SCHEMBL12798759 | 0.79 | SCN10A (0.52) | SCN10ACDC7CCNE1CDK2ROCK1 | |
| SCHEMBL12404403 | 0.79 | SCN10A (0.56) | SCN10ACDC7CCNE1CDK2ROCK1 | |
| SCHEMBL10201770 | 0.79 | SCN10A (0.41) | SCN10ACDC7CCNE1CDK2ROCK1 | |
| SCHEMBL13561572 | 0.78 | SCN10A (0.44) | SCN10ACDC7CCNE1CDK2ROCK1 | |
| SCHEMBL10200241 | 0.78 | TYMS (0.33) | TYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012018325-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-02-09 | — | — | WO | disclosed |