Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 2/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.38 |
| ▸ | CDK2 | P24941 | 2/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.38 |
| ▸ | DBF4 | Q9UBU7 | 2/20 | 0.38 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.35 |
| ▸ | TYMS | P04818 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10200249 | 0.85 | SCN10A (0.37) | CDC7CCNE1CDK2ROCK1DBF4 | |
| SCHEMBL19488529 | 0.83 | CDC7 (0.40) | CDC7CCNE1CDK2ROCK1DBF4 | |
| SCHEMBL12373613 | 0.81 | TYMS (0.33) | TYMS | |
| SCHEMBL10200243 | 0.80 | SCN10A (0.45) | CDC7CCNE1CDK2ROCK1DBF4 | |
| SCHEMBL12373600 | 0.79 | TYMS (0.33) | TYMS | |
| SCHEMBL10200241 | 0.79 | TYMS (0.33) | TYMS | |
| SCHEMBL19488788 | 0.78 | TYMS (0.32) | TYMS | |
| SCHEMBL19488785 | 0.77 | TYMS (0.31) | TYMS | |
| SCHEMBL13087671 | 0.74 | CDC7 (0.33) | CDC7CCNE1CDK2ROCK1DBF4 | |
| SCHEMBL10201148 | 0.70 | GABRG2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601188-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2017-10-18 | — | — | EP | disclosed |