Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 20/20 | 0.48 |
| ▸ | PGR | P06401 | 4/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14207525 | 0.92 | NR3C1 (0.47) | NR3C1PGRAR | |
| SCHEMBL14207921 | 0.91 | NR3C1 (0.46) | NR3C1PGRAR | |
| SCHEMBL764263 | 0.91 | NR3C1 (0.46) | NR3C1PGRAR | |
| SCHEMBL14207522 | 0.91 | NR3C1 (0.48) | NR3C1PGRAR | |
| SCHEMBL14207907 | 0.91 | NR3C1 (0.48) | NR3C1PGRAR | |
| SCHEMBL764975 | 0.91 | NR3C1 (0.48) | NR3C1PGRAR | |
| SCHEMBL14207927 | 0.89 | NR3C1 (0.46) | NR3C1PGRAR | |
| SCHEMBL752578 | 0.88 | NR3C1 (0.50) | NR3C1PGRAR | |
| SCHEMBL10332015 | 0.87 | NR3C1 (0.54) | NR3C1PGRAR | |
| SCHEMBL10331955 | 0.87 | NR3C1 (0.54) | NR3C1PGRAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2078015-B1 | MODULATORS OF GLUCOCORTICOID RECEPTOR, AP-1 AND/OR NF-KAPPAB ACTIVITY AND USE THEREOF | BRISTOL MYERS SQUIBB CO (US) | 2012-03-21 | — | — | EP | disclosed |
| WO-2008057859-A2 | MODULATORS OF GLUCOCORTICOID RECEPTOR, AP-I AND/OR NF-KAPPAB ACTIVITY AND USE THEREOF | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-05-15 | — | — | WO | disclosed |