Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | HPGDS | O60760 | 3/20 | 0.36 |
| ▸ | PRCP | P42785 | 2/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 3/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.32 |
| ▸ | CETP | P11597 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10182462 | 1.00 | USP30 (0.37) | USP30HPGDSPRCPHCRTR1HCRTR2 | |
| SCHEMBL12107333 | 0.85 | HPGDS (0.43) | HPGDSPRCPHCRTR1HCRTR2SSTR3 | |
| SCHEMBL14816986 | 0.85 | HPGDS (0.43) | HPGDSPRCPHCRTR1HCRTR2SSTR3 | |
| SCHEMBL824987 | 0.85 | HPGDS (0.43) | HPGDSPRCPHCRTR1HCRTR2SSTR3 | |
| SCHEMBL1293323 | 0.85 | HPGDS (0.43) | HPGDSPRCPHCRTR1HCRTR2SSTR3 | |
| SCHEMBL855831 | 0.85 | HPGDS (0.43) | HPGDSPRCPHCRTR1HCRTR2SSTR3 | |
| SCHEMBL1293325 | 0.85 | HPGDS (0.43) | HPGDSPRCPHCRTR1HCRTR2SSTR3 | |
| SCHEMBL12686992 | 0.85 | USP30 (0.40) | USP30HPGDSPRCPHCRTR1HCRTR2 | |
| SCHEMBL10182323 | 0.84 | USP30 (0.39) | USP30HPGDSHCRTR1HCRTR2AAK1 | |
| SCHEMBL1294320 | 0.84 | HPGDS (0.40) | USP30HPGDSPRCPHCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601188-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2017-10-18 | — | — | EP | disclosed |
| WO-2012018325-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-02-09 | — | — | WO | disclosed |