Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13221481 | 1.00 | NPC1 (0.36) | NPC1RAB9ASCN10ANPY5RAAK1 | |
| SCHEMBL19488500 | 0.92 | SCN10A (0.48) | NPC1RAB9ASCN10ANPY5R | |
| SCHEMBL19488598 | 0.86 | — | — | |
| SCHEMBL12373613 | 0.86 | TYMS (0.33) | — | |
| SCHEMBL12403377 | 0.86 | AAK1 (0.43) | NPC1RAB9ASCN10ANPY5RAAK1 | |
| SCHEMBL10201776 | 0.82 | SCN10A (0.53) | NPC1RAB9ASCN10ANPY5RKDM4E | |
| SCHEMBL10201772 | 0.81 | SCN10A (0.32) | NPC1RAB9ASCN10ANPY5R | |
| SCHEMBL13221474 | 0.81 | SCN10A (0.32) | NPC1RAB9ASCN10ANPY5R | |
| SCHEMBL19488530 | 0.80 | BACE1 (0.33) | NPY5RMAPTALDH1A1 | |
| SCHEMBL12403379 | 0.78 | MAPK1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012018325-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-02-09 | — | — | WO | disclosed |