Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 8/20 | 0.49 |
| ▸ | HCRTR2 | O43614 | 8/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PRCP | P42785 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10201222 | 0.90 | HCRTR1 (0.42) | HCRTR1HCRTR2PRCP | |
| SCHEMBL10201558 | 0.90 | HCRTR1 (0.41) | HCRTR1HCRTR2 | |
| SCHEMBL12404467 | 0.89 | HCRTR1 (0.57) | HCRTR1HCRTR2MAPTPOLBPRCP | |
| SCHEMBL2277418 | 0.88 | HCRTR1 (0.51) | HCRTR1HCRTR2MAPTPRCP | |
| SCHEMBL2277410 | 0.88 | HCRTR1 (0.51) | HCRTR1HCRTR2MAPTPRCP | |
| SCHEMBL10202424 | 0.87 | HCRTR1 (0.45) | HCRTR1HCRTR2MAPTPOLBPRCP | |
| SCHEMBL12799075 | 0.87 | PRCP (0.45) | HCRTR1HCRTR2PRCPUSP30 | |
| SCHEMBL12404479 | 0.86 | HCRTR1 (0.43) | HCRTR1HCRTR2MAPTPOLBPRCP | |
| SCHEMBL15896174 | 0.86 | HCRTR1 (0.43) | HCRTR1HCRTR2MAPTPOLBPRCP | |
| SCHEMBL10202512 | 0.86 | HCRTR1 (0.40) | HCRTR1HCRTR2PRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2398794-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2013-01-16 | — | — | EP | disclosed |
| WO-2012018325-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-02-09 | — | — | WO | disclosed |
| WO-2010096302-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-08-26 | — | — | WO | disclosed |