Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 17/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 17/20 | 0.41 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10202512 | 0.96 | HCRTR1 (0.40) | HCRTR1HCRTR2 | |
| SCHEMBL10202511 | 0.96 | HCRTR1 (0.39) | HCRTR1HCRTR2AADAT | |
| SCHEMBL10201817 | 0.92 | KCNH2 (0.39) | HCRTR1HCRTR2 | |
| SCHEMBL10201814 | 0.92 | PRCP (0.38) | HCRTR1HCRTR2 | |
| SCHEMBL12374143 | 0.92 | PRCP (0.38) | HCRTR1HCRTR2 | |
| SCHEMBL10201222 | 0.91 | HCRTR1 (0.42) | HCRTR1HCRTR2 | |
| SCHEMBL10202513 | 0.90 | KCNH2 (0.46) | HCRTR1HCRTR2 | |
| SCHEMBL10201223 | 0.90 | HCRTR1 (0.49) | HCRTR1HCRTR2 | |
| SCHEMBL2276310 | 0.87 | PRCP (0.38) | HCRTR1HCRTR2 | |
| SCHEMBL19488550 | 0.86 | HCRTR1 (0.42) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2398794-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2013-01-16 | — | — | EP | disclosed |
| WO-2012018325-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-02-09 | — | — | WO | disclosed |