SCHEMBL1020573

SCHEMBL1020573

[CH2]CNC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.61

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.61
EPHX2 P34913 1/20 0.56
FABP7 O15540 2/20 0.48
FABP5 Q01469 2/20 0.48
CASP3 P42574 2/20 0.46
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
MDM4 O15151 1/20 0.44
TP53 P04637 1/20 0.44
OPRD1 P41143 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6375583 0.88 KMT2A (0.66) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL30697177 0.86 KMT2A (0.63) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL16140731 0.86 KMT2A (0.63) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL7595024 0.85 KMT2A (0.70) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL1770756 0.84 KMT2A (0.61) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL17773317 0.84 KMT2A (0.68) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL21525041 0.84 KMT2A (0.61) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL30733150 0.84 KMT2A (0.61) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL19893094 0.84 KMT2A (0.73) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL6380797 0.84 KMT2A (0.62) KMT2AEPHX2FABP7FABP5CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110609078-A Method for detecting protein phosphorylation and acetylglucosamine saccharification correlation effect 南京谱利健生物技术有限公司 2019-12-24 CN claimed
EP-1140895-B1 THIOPYRAN COMPOUNDS AS INHIBITORS OF MMP FUJISAWA PHARMACEUTICAL CO (JP) 2004-03-24 EP claimed
WO-2003018019-A2 NEW USE OF CYCLIC COMPOUNDS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2003-03-06 WO claimed
EP-1140895-A2 THIOPYRAN COMPOUNDS AS INHIBITORS OF MMP FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2001-10-10 EP claimed
WO-2000040576-A2 THIOPYRAN COMPOUNDS AS INHIBITORS OF MMP FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2000-07-13 WO claimed
WO-2023109942-A1 COMPOUND-LINKER CONSTRUCTS COMPRISING NOVEL COMPOUNDS USEFUL AS STING AGONISTS AND USES THEREOF JACOBIO PHARMACEUTICALS CO., LTD. (CN) 2023-06-22 WO disclosed
CN-110609078-B Method for detecting protein phosphorylation and acetylglucosamine saccharification correlation effect 南京谱利健生物技术有限公司 2022-03-11 CN disclosed
WO-2021060496-A1 METHOD FOR IMPROVING PHOTOCLEAVAGE EFFICIENCY OF PHOTOCLEAVABLE LINKER, PHOTOCLEAVABLE LINKER-BOUND MAGNETIC PARTICLE, AND MEASUREMENT METHOD FOR MEASURING TARGET SUBSTANCE AND KIT FOR USE THEREWITH 富士レビオ株式会社 2021-04-01 WO disclosed
CN-110609078-A Method for detecting protein phosphorylation and acetylglucosamine saccharification correlation effect 南京谱利健生物技术有限公司 2019-12-24 CN disclosed
EP-3104893-A1 FACTOR VIII CONJUGATES Novo Nordisk A/S (DK) 2016-12-21 EP disclosed
EP-3104894-A1 FACTOR VII CONJUGATES Novo Nordisk Health Care AG (CH) 2016-12-21 EP disclosed
EP-3104892-A1 COAGULATION FACTOR IX CONJUGATES Novo Nordisk Health Care AG (CH) 2016-12-21 EP disclosed
EP-1140895-B1 THIOPYRAN COMPOUNDS AS INHIBITORS OF MMP FUJISAWA PHARMACEUTICAL CO (JP) 2004-03-24 EP disclosed
WO-2003068807-A2 ECHINOCANDIN CYCLIC PEPTIDE DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2003-08-21 WO disclosed
US-6608192-B1 Pyrrolobenzodiazepines SPIROGEN LIMITED (GB) 2003-08-19 US disclosed
WO-2002093131-A2 METHODS FOR ISOLATING AND LABELING SAMPLE MOLECULES THE INSTITUTE FOR SYSTEMS BIOLOGY (US) 2002-11-21 WO disclosed
EP-1140895-A2 THIOPYRAN COMPOUNDS AS INHIBITORS OF MMP FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2001-10-10 EP disclosed
EP-1107969-A2 COLLECTIONS OF COMPOUNDS Spirogen Limited (GB) 2001-06-20 EP disclosed
WO-2000040576-A2 THIOPYRAN COMPOUNDS AS INHIBITORS OF MMP FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2000-07-13 WO disclosed
WO-2000012506-A2 COLLECTIONS OF COMPOUNDS SPIROGEN LIMITED (GB) 2000-03-09 WO disclosed