Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | FABP7 | O15540 | 2/20 | 0.44 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19893094 | 0.96 | KMT2A (0.73) | KMT2AEPHX2FABP7FABP5CA1 | |
| SCHEMBL8762032 | 0.95 | KMT2A (0.75) | KMT2AEPHX2FABP7FABP5CA1 | |
| SCHEMBL6375583 | 0.92 | KMT2A (0.66) | KMT2AEPHX2FABP7FABP5CASP3 | |
| SCHEMBL5423087 | 0.91 | KMT2A (0.60) | KMT2AEPHX2FABP7FABP5CASP3 | |
| SCHEMBL793384 | 0.90 | KMT2A (0.85) | KMT2AEPHX2FABP7FABP5CASP3 | |
| SCHEMBL29468684 | 0.87 | KMT2A (0.72) | KMT2AEPHX2FABP7FABP5CASP3 | |
| SCHEMBL230688 | 0.87 | KMT2A (0.72) | KMT2AEPHX2FABP7FABP5CASP3 | |
| SCHEMBL31031901 | 0.87 | KMT2A (0.72) | KMT2AEPHX2FABP7FABP5CASP3 | |
| SCHEMBL19152620 | 0.86 | KMT2A (0.67) | KMT2AEPHX2FABP7FABP5CASP3 | |
| SCHEMBL23111835 | 0.86 | KMT2A (0.74) | KMT2AEPHX2FABP7FABP5CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859190-A | SOLID PHASE SYNTHESIS TO FORM A PROTECTED DIPEPTIDE FOLLOWED BY REACTING WITH 1,1'-THIOCARBONYLDIIMIDAZOLE TO EFFECT RING FORMATION; EFFICIENCY; ANTICONVULSANT,-ARRHYTHMIC AND DIABETIC AGENTS; HERBICIDES AND FUNGICIDES | TREGA BIOSCIENCES, INC. (US) | 1999-01-12 | — | — | US | claimed |
| WO-1998033776-A1 | COMBINATORIAL LIBRARIES OF HYDANTOIN AND THIOHYDANTOIN DERIVATIVES, METHODS OF MAKING THE LIBRARIES AND COMPOUNDS THEREIN | TREGA BIOSCIENCES, INC. (US) | 1998-08-06 | — | — | WO | claimed |
| EP-1259250-A1 | ENDOPARASITICIDAL AGENTS | Bayer Aktiengesellschaft (DE) | 2002-11-27 | — | — | EP | disclosed |
| WO-2001062268-A1 | ENDOPARASITICIDAL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2001-08-30 | — | — | WO | disclosed |
| WO-2000034226-A1 | POLYAMINE TRANSPORT INHIBITORS | UNIVERSITE LAVAL (CA) | 2000-06-15 | — | — | WO | disclosed |
| EP-1003715-A1 | POLYAMINE TRANSPORT INHIBITORS | UNIVERSITE LAVAL (CA) | 2000-05-31 | — | — | EP | disclosed |
| WO-1999054283-A1 | POLYAMINE TRANSPORT INHIBITORS | UNIVERSITE LAVAL (CA) | 1999-10-28 | — | — | WO | disclosed |
| US-5859190-A | SOLID PHASE SYNTHESIS TO FORM A PROTECTED DIPEPTIDE FOLLOWED BY REACTING WITH 1,1'-THIOCARBONYLDIIMIDAZOLE TO EFFECT RING FORMATION; EFFICIENCY; ANTICONVULSANT,-ARRHYTHMIC AND DIABETIC AGENTS; HERBICIDES AND FUNGICIDES | TREGA BIOSCIENCES, INC. (US) | 1999-01-12 | — | — | US | disclosed |
| EP-0876327-A2 | POLYAMINE TRANSPORT INHIBITORS | UNIVERSITE LAVAL (CA) | 1998-11-11 | — | — | EP | disclosed |
| WO-1998033776-A1 | COMBINATORIAL LIBRARIES OF HYDANTOIN AND THIOHYDANTOIN DERIVATIVES, METHODS OF MAKING THE LIBRARIES AND COMPOUNDS THEREIN | TREGA BIOSCIENCES, INC. (US) | 1998-08-06 | — | — | WO | disclosed |
| WO-1998017623-A2 | POLYAMINE TRANSPORT INHIBITORS | UNIVERSITE LAVAL (US) | 1998-04-30 | — | — | WO | disclosed |
| US-5571793-A | COMBATTING ENDOPARASITES IN HUMANS OR ANIMALS BY ADMINISTERING PEPTIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-11-05 | — | — | US | disclosed |
| US-5529984-A | NEMATOCIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-06-25 | — | — | US | disclosed |
| WO-1995027498-A1 | USE OF CYCLIC DEPSIPEPTIDES WITH 18 RING ATOMS | BAYER AKTIENGESELLSCHAFT (DE) | 1995-10-19 | — | — | WO | disclosed |