Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4568747 | 0.98 | TSHR (0.37) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL15836525 | 0.84 | TSHR (0.34) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL21013008 | 0.84 | TSHR (0.34) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL1602185 | 0.81 | TSHR (0.35) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| Ammonia Solution, Strong SCHEMBL1020874 | 0.80 | TSHR (0.38) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| Ammonia Solution, Strong SCHEMBL1707597 | 0.80 | TSHR (0.38) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL4465024 | 0.79 | TSHR (0.34) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL9788881 | 0.78 | TSHR (0.37) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| Hydrochloric Acid SCHEMBL18091194 | 0.78 | TSHR (0.37) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL7718060 | 0.78 | TSHR (0.37) | TSHRALDH1A1TP53HIF1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924235-A2 | ADHESIVE AND METHOD FOR BONDING ARTIFICIAL PLASTIC TEETH | DENTSPLY INTERNATIONAL, INC. (US) | 2008-05-28 | — | — | EP | claimed |
| WO-2007022503-A2 | ADHESIVE AND METHOD FOR BONDING ARTIFICIAL PLASTIC TEETH | DENTSPLY INTERNATIONAL INC. (US) | 2007-02-22 | — | — | WO | claimed |
| EP-2642967-B1 | HIGH STRENGTH DENTAL MATERIAL | DENTSPLY SIRONA INC (US) | 2023-08-02 | — | — | EP | disclosed |
| EP-2066258-B1 | METHODS OF MANUFACTURING DENTAL APPLIANCES USING SURFACE TREATING COMPOSITIONS | DENTSPLY INT INC (US) | 2016-11-30 | — | — | EP | disclosed |
| EP-2073750-B1 | Method for making provisional and long-term dental restorations | DENTSPLY INT INC (US) | 2016-04-13 | — | — | EP | disclosed |
| EP-1677741-B1 | DENTAL METHOD AND DEVICE | DENTSPLY INT INC (US) | 2014-10-01 | — | — | EP | disclosed |
| EP-2642967-A2 | HIGH STRENGTH DENTAL MATERIAL | Dentsply International Inc. (US) | 2013-10-02 | — | — | EP | disclosed |
| WO-2012071329-A2 | HIGH STRENGTH DENTAL MATERIAL | DENTSPLY INTERNATIONAL INC (US) | 2012-05-31 | — | — | WO | disclosed |
| EP-1924235-B1 | METHOD FOR BONDING ARTIFICIAL PLASTIC TEETH | DENTSPLY INT INC (US) | 2011-01-12 | — | — | EP | disclosed |
| US-7566412-B2 | Dental method and device | DENTSPLY INTERNATIONAL INC. (US) | 2009-07-28 | — | — | US | disclosed |
| EP-1924235-A2 | ADHESIVE AND METHOD FOR BONDING ARTIFICIAL PLASTIC TEETH | DENTSPLY INTERNATIONAL, INC. (US) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007022503-A2 | ADHESIVE AND METHOD FOR BONDING ARTIFICIAL PLASTIC TEETH | DENTSPLY INTERNATIONAL INC. (US) | 2007-02-22 | — | — | WO | disclosed |