Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | ACACB | O00763 | 5/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
| ▸ | ACACA | Q13085 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CKS1B | P61024 | 1/20 | 0.44 |
| ▸ | SKP1 | P63208 | 1/20 | 0.44 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL60318 | 0.98 | EPHX1 (0.56) | EPHX1KMT2ADRD2ACACBCTSS | |
| SCHEMBL228180 | 0.96 | EPHX1 (0.50) | EPHX1KMT2ADRD2ACACBCTSS | |
| Bicarbonate SCHEMBL5780143 | 0.95 | EPHX1 (0.54) | EPHX1KMT2ADRD2ACACBCTSS | |
| Acetic Acid SCHEMBL3275951 | 0.93 | EPHX1 (0.52) | EPHX1KMT2ADRD2ACACBCTSS | |
| SCHEMBL3942686 | 0.92 | KMT2A (0.56) | EPHX1KMT2ADRD2ACACBCTSS | |
| SCHEMBL3816616 | 0.92 | KMT2A (0.56) | EPHX1KMT2ADRD2ACACBCTSS | |
| SCHEMBL4377073 | 0.92 | KMT2A (0.56) | EPHX1KMT2ADRD2ACACBCTSS | |
| SCHEMBL190838 | 0.92 | KMT2A (0.56) | EPHX1KMT2ADRD2ACACBCTSS | |
| SCHEMBL17109668 | 0.91 | EPHX1 (0.50) | EPHX1KMT2ADRD2ACACBCTSS | |
| SCHEMBL6647123 | 0.89 | EPHX1 (0.48) | EPHX1KMT2ADRD2ACACBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026107208-A1 | COMPOSITIONS AND METHODS FOR TREATING MICROBIAL INFECTIONS | THE METHODIST HOSPITAL (US) | 2026-05-21 | — | — | WO | disclosed |
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |
| CN-107417707-A | 1H pyrazolos [3,4 b] pyridine and its treatment use | 萨穆梅德有限公司 | 2017-12-01 | — | — | CN | disclosed |
| CN-104271133-B | 1H-pyrazolo [3,4-b ] pyridines and therapeutic uses thereof | 萨穆梅德有限公司 | 2017-10-13 | — | — | CN | disclosed |
| CN-106892916-A | The indazole inhibitors and its treatment use of WNT signal paths | 萨穆梅德有限公司 | 2017-06-27 | — | — | CN | disclosed |
| CN-104202984-B | Indazole inhibitors of the WNT signaling pathway and therapeutic uses thereof | 萨穆梅德有限公司 | 2017-04-05 | — | — | CN | disclosed |
| CN-103254190-B | Heteroaryl substituted pyrrolo-[2,3-b] pyridine and pyrrolo-[2,3-b] pyrimidine as Janus inhibitors of kinases | 因塞特控股公司 | 2016-12-07 | — | — | CN | disclosed |
| US-9206142-B2 | Anilinopiperazine derivatives and methods of use thereof | MERCK SHARP & DOHME CORP. (US) | 2015-12-08 | — | — | US | disclosed |
| CN-104271133-A | 1H-pyrazolo [3,4-b ] pyridines and therapeutic uses thereof | SAMUMED LLC | 2015-01-07 | — | — | CN | disclosed |
| CN-104202984-A | Indazole inhibitors of the WNT signaling pathway and therapeutic uses thereof | SAMUMED LLC | 2014-12-10 | — | — | CN | disclosed |
| US-8835461-B2 | Substituted 3-hydroxy-4-pyridone derivative | SHIONOGI & CO., LTD. (JP) | 2014-09-16 | — | — | US | disclosed |
| US-20120328691-A1 | ANILINOPIPERAZINE DERIVATIVES AND METHODS OF USE THEREOF | MERCK SHARP & DOHME LLC | 2012-12-27 | — | — | US | disclosed |
| US-20120058989-A1 | ANTIBACTERIAL FLUOROQUINOLONE ANALOGS | ACHAOGEN, INC. (US) | 2012-03-08 | — | — | US | disclosed |
| US-20120022255-A1 | SUBSTITUTED 3-HYDROXY-4-PYRIDONE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022255-A1 | SUBSTITUTED 3-HYDROXY-4-PYRIDONE DERIVATIVE | ENDOD1, CNBP, DPP4 | EPHX1 758/4885KMT2A 3094/4885DRD2 3718/4885 |
| US-20120058989-A1 | ANTIBACTERIAL FLUOROQUINOLONE ANALOGS | RECQL, BLVRB, NQO2 | EPHX1 2310/4885KMT2A 4780/4885DRD2 198/4885 |
| US-20120328691-A1 | ANILINOPIPERAZINE DERIVATIVES AND METHODS OF USE THEREOF | MAPK15, CDK15, MAPKAPK5 | EPHX1 3954/4885KMT2A 3820/4885DRD2 3597/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.