BLVRB

Flavin reductase (NADPH) · P30043 · BLVRB on Sugi Atlas →

6,299 patent compounds predicted against BLVRB, 5,231 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL137145	0.85	2/20
SCHEMBL137146	0.85	2/20
SCHEMBL130906	0.76	2/20
SCHEMBL1636172	0.72	2/20
SCHEMBL1636173	0.72	2/20
SCHEMBL133646	0.70	2/20
SCHEMBL133647	0.70	2/20
SCHEMBL1636562	0.68	2/20
SCHEMBL1636563	0.68	2/20
Salazodine (SCHEMBL1224095)	0.66	2/20
Olsalazine (SCHEMBL29767)	0.66	2/20
SCHEMBL497248	0.65	2/20
Ipsalazide (SCHEMBL596652)	0.62	2/20
Salazosulfadimidine (SCHEMBL150333)	0.62	2/20
SCHEMBL596802	0.60	2/20
SCHEMBL596803	0.60	2/20
Balsalazide (SCHEMBL118300)	0.59	2/20
Balsalazide (SCHEMBL138311)	0.59	2/20
Balsalazide (SCHEMBL134019)	0.57	2/20
Balsalazide (SCHEMBL133200)	0.56	2/20

Clinical trials — most relevant to BLVRB by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Effects of Tetrahydrobiopterin (BH4) on Leg Blood Flow and Exercise Capacity in Patients With Peripheral Artery Disease	PHASE4	WITHDRAWN
Phase II Study of Simvastatin Plus Irinotecan, Fluorouracil, and Leucovorin(FOLFIRI) for Metastatic CRC	PHASE2	COMPLETED
Oral Propranolol Versus Placebo for Early Stages of Retinopathy of Prematurity: A Randomized and Prospective Study	PHASE1/PHASE2	COMPLETED
Nitrite Infusion Studies	PHASE1	COMPLETED
The Effect of Antioxidants on Skin Blood Flow-BH4	PHASE1	COMPLETED
Novel Approaches for Improving Vascular Function in Veterans With HFpEF	PHASE1	RECRUITING
Safety, Tolerability and Pharmacokinetics of Benfo-Oxythiamine (B-OT) in Healthy Volunteers	PHASE1	COMPLETED
Forced Oscillometry in Infants With Bronchopulmonary Dysplasia	nan	RECRUITING
Droplet Digital PCR and PCR-free BIOSensors for the Detection of Resistance-associated SNPs in Pneumocystis Jirovecii	nan	ACTIVE_NOT_RECRUITING
The Effect of Raising Ketones Directly With MCT Oil on Inflammation in Healthy Young Adults	nan	COMPLETED
Mechanisms of Inherited Retinal Dystrophies Using Whole Genome Sequencing and in Vitro and in Vivo Models	nan	COMPLETED
Plant-based Diets and Body Weight and Selected Metabolic Parameters Management in Obese Patients.	nan	COMPLETED
Study of Genotype and Phenotype Characterization in Duchenne Muscular Dystrophy With Small Mutations	nan	UNKNOWN
Characterizing a 5P-Linked BHR Susceptibility Locus	nan	COMPLETED
Clinical and Genetic Studies of Familial Exudative Vitreoretinopathy	nan	COMPLETED
Genetic Association of Diabetic Retinopathy-1	nan	UNKNOWN
Ataxia-telangiectasia: Treating Mitochondrial Dysfunction With Nicotinamide Riboside	nan	UNKNOWN
Sodium Transport: Genetics and Hypertension	nan	COMPLETED
Identifying Genes and Mutations Underlying Retinitis Pigmentosa and Allied Diseases	nan	UNKNOWN
A Proof of Concept Study for the DNA Repair Driven by the Mesenchymal Stem Cells in Critical COVID-19 Patients	nan	COMPLETED
Golimumab Effect in the Modulation of Gut Microbiota in Ulcerative Colitis	nan	COMPLETED
Studying Tissue Samples From Patients With Stage II Colon Cancer Treated on Clinical Trial CLB-9581	nan	COMPLETED
Identification of Acute Intermittent Porphyria Modifying Genes	nan	RECRUITING
Dietary and Genetic Factors in Asthma & Chronic Bronchitis in a Cohort of Chinese Singaporeans	nan	COMPLETED
Molecular Genetics of Retinal Degenerations	nan	COMPLETED
Role of Metabolic Enzymes in Non-Melanoma Skin Cancer	nan	COMPLETED
Central Serous Chorioretinopathy Registry and Pachychoroid Observation and Natural History Study	nan	UNKNOWN
Genetics of Asthma and Bronchial Hyperresponsiveness	nan	COMPLETED
Genes Associated With Bronchopulmonary Dysplasia and Retinopathy of Prematurity	nan	COMPLETED
Genetic Mechanisms of Chronic Obstructive Pulmonary Disease (COPD)	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a BLVRB binder may also engage these)

Protein	Name	Similarity
P52556	—	0.998	P52556 →
Q923D2	—	0.988	Q923D2 →
Q94EG6	—	0.961	Q94EG6 →
Q0VCN1	—	0.955	Q0VCN1 →
NMRAL1	NmrA-like family domain-containing protein 1	0.951	landscape →
Q5ZID0	—	0.947	Q5ZID0 →
Q9I6Z2	—	0.945	Q9I6Z2 →
P35340	—	0.945	P35340 →
A0PJE2	—	0.944	A0PJE2 →
Q8K2T1	—	0.943	Q8K2T1 →
D5JWB3	—	0.943	D5JWB3 →
P0A156	—	0.940	P0A156 →
Q8R1G2	—	0.940	Q8R1G2 →
P0A155	—	0.940	P0A155 →
A6QP05	—	0.939	A6QP05 →
P19480	—	0.939	P19480 →
O06465	—	0.939	O06465 →
Q53JY8	—	0.938	Q53JY8 →
P15904	—	0.938	P15904 →
P37791	—	0.938	P37791 →
C5B9M4	—	0.937	C5B9M4 →
B4EUU7	—	0.937	B4EUU7 →
B5Y0W8	—	0.937	B5Y0W8 →
Q14353	—	0.937	Q14353 →
Q5RBE5	—	0.936	Q5RBE5 →
Q67WR2	—	0.936	Q67WR2 →
A8GAD0	—	0.936	A8GAD0 →
A2QS05	—	0.935	A2QS05 →
B4SWR7	—	0.935	B4SWR7 →
A0A1C9CX66	—	0.935	A0A1C9CX66 →