SCHEMBL1021060

SCHEMBL1021060

O=C1CCC=C1C1CCCC1

nearest known ligand 0.56

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.56
MAOA P21397 1/20 0.42
MAOB P27338 1/20 0.42
PTPN1 P18031 2/20 0.36
PTPRC P08575 1/20 0.35
PTPRF P10586 1/20 0.35
CDC25B P30305 1/20 0.35
HIF1A Q16665 1/20 0.34
CCR2 P41597 1/20 0.34
DAO P14920 2/20 0.32
GAA P10253 1/20 0.31
RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1238056 0.98 MAPT (0.55) MAPTMAOAMAOBPTPN1PTPRC
SCHEMBL1237586 0.89 MAPT (0.70) MAPTMAOAMAOBPTPN1PTPRC
SCHEMBL3397911 0.87 MAPT (0.62) MAPTMAOAMAOBPTPN1PTPRC
SCHEMBL1235852 0.87 MAPT (0.68) MAPTMAOAMAOBPTPN1PTPRC
SCHEMBL11181983 0.84 MAPT (0.65) MAPTMAOAMAOBPTPN1PTPRC
SCHEMBL900953 0.84 MAPT (0.70) MAPTMAOAMAOBPTPN1PTPRC
SCHEMBL6911275 0.84 MAPT (0.59) MAPTMAOAMAOBPTPN1PTPRC
SCHEMBL10975426 0.77
SCHEMBL14763707 0.74 MAPT (0.57) MAPTHIF1ACCR2DAO
SCHEMBL30235867 0.72 MAPT (0.37) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240409486-A1 COMPOUND PRODUCING METHOD INCLUDING STEP OF ISOMERIZING ALPHA, BETA-UNSATURATED KETONE KAO CORPORATION (JP) 2024-12-12 US disclosed
CN-118103345-A Method for producing compound comprising isomerization step of alpha, beta-unsaturated ketone 花王株式会社 2024-05-28 CN disclosed
WO-2023063030-A1 COMPOUND PRODUCING METHOD INCLUDING STEP FOR ISOMERIZING α,β-UNSATURATED KETONE 花王株式会社 2023-04-20 WO disclosed
EP-2266943-B1 METHOD FOR PRODUCING OF 2-ALKYL-2-CYCLOALKEN-1-ONE KAO CORP (JP) 2016-11-16 EP disclosed
US-8394994-B2 Method for producing of 2-alkyl-2-cycloalken-1-one KAO CORPORATION (JP) 2013-03-12 US disclosed
US-20110034722-A1 METHOD FOR PRODUCING OF 2-ALKYL-2-CYCLOALKEN-1-ONE KAO CORPORATION (JP) 2011-02-10 US disclosed
EP-1841729-B1 2-CYCLOPENTEN-1-ONE OXIME DERIVATIVES INHIBITING PRODUCTION OF TNF-ALPHA AMOREPACIFIC CORP (KR) 2011-01-12 EP disclosed
EP-2266943-A1 METHOD FOR PRODUCING OF 2-ALKYL-2-CYCLOALKEN-1-ONE Kao Corporation (JP) 2010-12-29 EP disclosed
US-3981911-A Process for preparing (1-oxo-2-cyclopentyl-2-methyl-6,7-dichloro-5-indanyloxy)acetic acid MERCK & CO., INC. (US) 1976-09-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240409486-A1 COMPOUND PRODUCING METHOD INCLUDING STEP OF ISOMERIZING ALPHA, BETA-UNSATURATED KETONE CBR1, AKR1B1, AKR1C1 MAPT 4276/4885MAOA 2548/4885MAOB 1511/4885
US-20110034722-A1 METHOD FOR PRODUCING OF 2-ALKYL-2-CYCLOALKEN-1-ONE PAOX, CYP1A1, ADH1A MAPT 4431/4885MAOA 816/4885MAOB 2472/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.