Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 4/20 | 0.33 |
| ▸ | CNR1 | P21554 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1024786 | 0.99 | TSHR (0.48) | TSHRTDP1PPARGPPARAFAAH | |
| SCHEMBL1021566 | 0.99 | TSHR (0.48) | TSHRTDP1PPARGPPARAFAAH | |
| SCHEMBL1309265 | 0.99 | TSHR (0.48) | TSHRTDP1PPARGPPARAFAAH | |
| SCHEMBL1021119 | 0.97 | TSHR (0.50) | TSHRTDP1PPARGPPARAFAAH | |
| SCHEMBL2928078 | 0.95 | TSHR (0.45) | TSHRTDP1PPARGPPARAFAAH | |
| SCHEMBL2933085 | 0.94 | TSHR (0.44) | TSHRTDP1PPARGPPARAHTT | |
| SCHEMBL2927090 | 0.94 | TSHR (0.44) | TSHRTDP1PPARGPPARAHTT | |
| SCHEMBL2929542 | 0.94 | TSHR (0.44) | TSHRTDP1PPARGPPARAHTT | |
| SCHEMBL2929507 | 0.92 | TSHR (0.46) | TSHRTDP1PPARGPPARAFAAH | |
| SCHEMBL1021356 | 0.92 | TSHR (0.52) | TSHRTDP1FAAHMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8053595-B2 | Process for producing isocyanates | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2011-11-08 | — | — | US | disclosed |
| EP-2088137-B1 | A PROCESS FOR PRODUCING ISOCYANATES | ASAHI KASEI CHEMICALS CORP (JP) | 2011-01-12 | — | — | EP | disclosed |