Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2929435 | 0.94 | TSHR (0.47) | TSHRTDP1MEN1KMT2AFAAH | |
| SCHEMBL1021119 | 0.93 | TSHR (0.50) | TSHRTDP1MEN1KMT2ANPC1 | |
| SCHEMBL1021096 | 0.92 | TSHR (0.49) | TSHRTDP1MEN1KMT2ANPC1 | |
| SCHEMBL1309265 | 0.91 | TSHR (0.48) | TSHRTDP1FAAHEPHX1 | |
| SCHEMBL1024786 | 0.91 | TSHR (0.48) | TSHRTDP1FAAHEPHX1 | |
| SCHEMBL1021566 | 0.91 | TSHR (0.48) | TSHRTDP1FAAHEPHX1 | |
| SCHEMBL1021773 | 0.89 | TSHR (0.55) | TSHRTDP1MEN1KMT2ANPC1 | |
| SCHEMBL1023557 | 0.87 | TSHR (0.55) | TSHRTDP1 | |
| SCHEMBL990592 | 0.87 | TSHR (0.55) | TSHRTDP1RAB9AEPHX1POLB | |
| SCHEMBL2929507 | 0.87 | TSHR (0.46) | TSHRTDP1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8053595-B2 | Process for producing isocyanates | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2011-11-08 | — | — | US | disclosed |
| EP-2088137-B1 | A PROCESS FOR PRODUCING ISOCYANATES | ASAHI KASEI CHEMICALS CORP (JP) | 2011-01-12 | — | — | EP | disclosed |