Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | EZH2 | Q15910 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2930878 | 0.95 | TSHR (0.49) | TSHREZH2TDP1USP2POLB | |
| SCHEMBL1022837 | 0.91 | TSHR (0.49) | TSHREZH2TDP1EPHX1USP2 | |
| SCHEMBL2923735 | 0.86 | TSHR (0.46) | TSHREZH2TDP1POLBGAA | |
| SCHEMBL1952647 | 0.86 | TSHR (0.55) | TSHREZH2TDP1POLBCHRM2 | |
| SCHEMBL2930879 | 0.85 | KCNA3 (0.37) | TSHREZH2KCNA3GAACHRM2 | |
| SCHEMBL1836071 | 0.84 | TSHR (0.57) | TSHRTDP1EPHX1USP2HCRTR2 | |
| SCHEMBL29914212 | 0.83 | TSHR (0.59) | TSHREZH2TDP1EPHX1USP2 | |
| SCHEMBL982145 | 0.83 | TSHR (0.59) | TSHREZH2TDP1EPHX1USP2 | |
| SCHEMBL1953150 | 0.83 | TSHR (0.51) | TSHREZH2HTTKDM4EKMT2A | |
| SCHEMBL989495 | 0.83 | TSHR (0.58) | TSHREZH2TDP1EPHX1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8053595-B2 | Process for producing isocyanates | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2011-11-08 | — | — | US | disclosed |
| EP-2088137-B1 | A PROCESS FOR PRODUCING ISOCYANATES | ASAHI KASEI CHEMICALS CORP (JP) | 2011-01-12 | — | — | EP | disclosed |