Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | LHCGR | P22888 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL982145 | 0.87 | TSHR (0.59) | TSHREPHX1TDP1USP2MEN1 | |
| SCHEMBL29914212 | 0.87 | TSHR (0.59) | TSHREPHX1TDP1USP2MEN1 | |
| SCHEMBL1840943 | 0.86 | TSHR (0.58) | TSHREPHX1FAAHLHCGR | |
| SCHEMBL989495 | 0.86 | TSHR (0.58) | TSHREPHX1TDP1USP2HCRTR2 | |
| SCHEMBL983463 | 0.85 | TSHR (0.63) | TSHRFAAHLHCGR | |
| SCHEMBL6526426 | 0.84 | TSHR (0.55) | TSHRTDP1USP2MEN1KMT2A | |
| SCHEMBL1021098 | 0.84 | TSHR (0.53) | TSHREPHX1TDP1USP2KDM4E | |
| SCHEMBL990592 | 0.83 | TSHR (0.55) | TSHREPHX1TDP1USP2GAA | |
| SCHEMBL1953902 | 0.83 | TSHR (0.57) | TSHREPHX1TDP1USP2MEN1 | |
| SCHEMBL30409767 | 0.83 | TSHR (0.57) | TSHREPHX1TDP1USP2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2322504-A1 | PROCESS FOR THE PREPARATION OF N-SUBSTITUTED CARBAMIC ACID ESTER AND PROCESS FOR THE PREPARATION OF ISOCYANATE USING THE N-SUBSTITUTED CARBAMIC ACID ESTER | Asahi Kasei Chemicals Corporation (JP) | 2011-05-18 | — | — | EP | disclosed |