Sugi Predict

Sugi Predict / Compounds / SCHEMBL102120

SCHEMBL102120

SCHEMBL102120

COc1cccc(Cl)c1[N+](=O)[O-]

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 4/20 0.53
▸ ALDH1A1 P00352 4/20 0.53
▸ TLR8 Q9NR97 1/20 0.48
▸ HPGD P15428 4/20 0.47
▸ L3MBTL1 Q9Y468 2/20 0.47
▸ MAPT P10636 6/20 0.47
▸ LMNA P02545 4/20 0.47
▸ SMN1; SMN2 Q16637 3/20 0.47
▸ PIN1 Q13526 1/20 0.47
▸ KDM4E B2RXH2 2/20 0.46
▸ POLB P06746 1/20 0.46
▸ CTDSP1 Q9GZU7 1/20 0.46
▸ NPC1 O15118 1/20 0.46
▸ CYP1A2 P05177 1/20 0.46
▸ CYP3A4 P08684 1/20 0.46
▸ CYP2D6 P10635 1/20 0.46
▸ CYP2C9 P11712 1/20 0.46
▸ CYP2C19 P33261 1/20 0.46
▸ RAB9A P51151 1/20 0.46
▸ BLM P54132 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11497261 0.86 HPGD (0.58) TDP1ALDH1A1TLR8HPGDL3MBTL1
SCHEMBL1961457 0.86 TDP1 (0.63) TDP1ALDH1A1HPGDL3MBTL1KDM4E
SCHEMBL9816760 0.83 HPGD (0.47) TDP1ALDH1A1TLR8HPGDL3MBTL1
SCHEMBL16174884 0.83 MAPT (0.54) TDP1ALDH1A1HPGDL3MBTL1MAPT
SCHEMBL10499693 0.82 KMT2A (0.51) TDP1ALDH1A1TLR8HPGDL3MBTL1
Methyl Alcohol SCHEMBL27781923 0.82 TDP1 (0.59) TDP1ALDH1A1HPGDL3MBTL1MAPT
SCHEMBL10499780 0.81 ACHE (0.44) TDP1ALDH1A1TLR8HPGDMAPT
SCHEMBL670917 0.81 TSHR (0.58) TDP1ALDH1A1TLR8HPGDLMNA
SCHEMBL1982757 0.80 TLR8 (0.45) TDP1ALDH1A1TLR8HPGDL3MBTL1
SCHEMBL11489993 0.80 TLR8 (0.45) TDP1ALDH1A1TLR8HPGDL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118834217-A Pyrano [2,3-a ] phenazine derivative, and preparation method and application thereof 中国药科大学 2024-10-25 — — CN claimed
CN-109265350-A The synthetic method of acaricide Bifenazate intermediate 3- nitro -4- methoxyl biphenyl 山东省农药科学研究院 2019-01-25 — — CN claimed
CN-107523996-A A kind of anti-oxidant xanthochromia finishing agent and preparation method thereof 南通冠洲国际贸易有限公司 2017-12-29 — — CN claimed
CN-107401047-A The anti-yellowing finishing agent and its preparation technology of a kind of light fabric 南通冠洲国际贸易有限公司 2017-11-28 — — CN claimed
CN-105648759-A Anti-oxidation finishing agent for textiles and preparation method of anti-oxidation finishing agent 吴江市泽旺纺织有限公司 2016-06-08 — — CN claimed
EP-1016405-A2 Arylating medicaments Radopath Pharmaceuticals International Limited (GB) 2000-07-05 — — EP claimed
EP-0700287-A1 ARYLATING MEDICAMENTS RADOPATH LIMITED (GB) 1996-03-13 — — EP claimed
WO-1994027584-A2 ARYLATING MEDICAMENTS RADOPATH LIMITED (GB) 1994-12-08 — — WO claimed
US-4473713-A Hydrolysis of aryl-aliphatic ethers RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1984-09-25 — — US claimed
WO-2026105856-A1 ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT キヤノン株式会社 2026-05-21 — — WO disclosed
WO-2024222814-A1 CYP11B2 INHIBITOR COMPOUND, PHARMACEUTICAL COMPOSITION AND USE THEREOF 长春金赛药业有限责任公司 2024-10-31 — — WO disclosed
CN-109912437-A A kind of polyamine monomers and preparation method thereof, a kind of polyimides and preparation method thereof and a kind of Kapton 吉林大学 2019-06-21 — — CN disclosed
CN-109265350-A The synthetic method of acaricide Bifenazate intermediate 3- nitro -4- methoxyl biphenyl 山东省农药科学研究院 2019-01-25 — — CN disclosed
CN-108277634-A A kind of swimming suit fabric and its manufacturing process 于美花 2018-07-13 — — CN disclosed
US-20090124625-A1 NOVEL ALKYNYL DERIVATIVES AS MODULATORS OF METATROPIC GLUTAMATE RECEPTORS ADDEX PHARMACEUTICALS SA (CH) 2009-05-14 — — US disclosed
EP-1765795-A2 ALKYNYL DERIVATIVES AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS Addex Pharmaceuticals SA (CH) 2007-03-28 — — EP disclosed
WO-2005123703-A2 ALKYNYL DERIVATIVES AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS ADDEX PHARMACEUTICALS SA (CH) 2005-12-29 — — WO disclosed
US-4473713-A Hydrolysis of aryl-aliphatic ethers RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1984-09-25 — — US disclosed
US-4224248-A Process for the depyrophorization of pyrophoric metal catalysts and uses thereof BAYER AKTIENGESELLSCHAFT (DE) 1980-09-23 — — US disclosed
US-4176092-A TREATMENT WITH AN ORGANIC NITRO OR A NITROSO COMPOUND BAYER AKTIENGESELLSCHAFT (DE) 1979-11-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090124625-A1 NOVEL ALKYNYL DERIVATIVES AS MODULATORS OF METATROPIC GLUTAMATE RECEPTORS GRM5, GRM2, GRM1 TDP1 3469/4885ALDH1A1 2496/4885TLR8 1225/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.