Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | HMGCR | P04035 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10308344 | 0.78 | KDM4E (0.33) | PIK3CDHMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL7910108 | 0.78 | HMGCR (0.33) | PIK3CDHMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL7917694 | 0.76 | PIK3CD (0.46) | PIK3CDHMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL13201626 | 0.75 | — | — | |
| SCHEMBL18264641 | 0.74 | CYP2C19 (0.32) | PIK3CDHMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL22253948 | 0.74 | PIK3CD (0.31) | PIK3CDHMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL10212340 | 0.74 | PIK3CD (0.31) | PIK3CDHMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL17449479 | 0.74 | PIK3CD (0.35) | PIK3CDHMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL10212341 | 0.74 | PIK3CD (0.31) | PIK3CDHMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL5693007 | 0.72 | ALDH1A1 (0.31) | PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170096446-A1 | Extended Triterpene Derivatives | MYREXIS, INC. (US) | 2017-04-06 | — | — | US | disclosed |
| US-9505800-B2 | Extended triterpene derivatives | MYREXIS, INC. (US) | 2016-11-29 | — | — | US | disclosed |
| US-20120046291-A1 | Extended Triterpene Derivatives | MYREXIS, INC. | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170096446-A1 | Extended Triterpene Derivatives | BET1, PGGT1B, TMPO | PIK3CD 582/4885HMGCR 254/4885CHRM1 3305/4885 |
| US-20120046291-A1 | Extended Triterpene Derivatives | BET1, PGGT1B, TMPO | PIK3CD 582/4885HMGCR 254/4885CHRM1 3305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.