⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL106244 | 0.80 | — | — | |
| SCHEMBL1108358 | 0.80 | — | — | |
| SCHEMBL16776729 | 0.80 | CD44 (0.72) | — | |
| SCHEMBL3395495 | 0.78 | CYP2A6 (0.43) | — | |
| Ammonia Solution, Strong SCHEMBL1289383 | 0.77 | CD44 (0.68) | — | |
| Bromide SCHEMBL28370305 | 0.77 | CD44 (0.68) | — | |
| Lithium SCHEMBL30421931 | 0.77 | CD44 (0.68) | — | |
| SCHEMBL30355145 | 0.77 | CD44 (0.68) | — | |
| Bromide SCHEMBL28506748 | 0.77 | CD44 (0.68) | — | |
| SCHEMBL6687694 | 0.77 | CD44 (0.68) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119707773-A | Preparation method and application of maleimide structure-containing compound | 中国农业大学 | 2025-03-28 | — | — | CN | claimed |
| CN-105016963-A | Synthetic method of 2-bromo-5-iodotoluene | JIANGSU VICITORIES CHEMICALS CO LTD | 2015-11-04 | — | — | CN | claimed |
| CN-1946675-A | Separation of amine from a phenolic compound | DU PONT (US) | 2007-04-11 | — | — | CN | claimed |
| CN-119707773-A | Preparation method and application of maleimide structure-containing compound | 中国农业大学 | 2025-03-28 | — | — | CN | disclosed |
| CN-110036014-A | A kind of compound and its preparation and application with AXL inhibitory activity | 中国科学院上海药物研究所 | 2019-07-19 | — | — | CN | disclosed |
| CN-109890827-A | Spiro-compound | 芝诺罗耶尔蒂里程碑有限责任公司 | 2019-06-14 | — | — | CN | disclosed |
| CN-109761904-A | A kind of synthetic method of the iodo- 1H- indazole of 6- | 安徽诺全药业有限公司 | 2019-05-17 | — | — | CN | disclosed |
| CN-108884106-A | POLYCYCLIC COMPOUNDS AS INHIBITORS OF BRUTON'S TYROSINE KINASE | 詹森药业有限公司 | 2018-11-23 | — | — | CN | disclosed |
| CN-108250200-A | A kind of compound and its preparation and application with Axl inhibitory activity | 中国科学院上海药物研究所 | 2018-07-06 | — | — | CN | disclosed |
| CN-108147972-A | A kind of preparation method of Wei Patawei intermediates and the like | 成都西岭源药业有限公司 | 2018-06-12 | — | — | CN | disclosed |
| CN-107109212-A | Power mutagens color luminescent material, make the power mutagens color luminescent material be crosslinked obtained by power mutagens chromoresin and the manufacture method of the two | 国立研究开发法人科学技术振兴机构 | 2017-08-29 | — | — | CN | disclosed |
| CN-103122000-B | High-selectivity c-Met kinase inhibitor used as antitumor drug | CROWN BIOSCIENCE TAICANG INC | 2013-12-25 | — | — | CN | disclosed |
| US-20120028959-A1 | DIHYDROOROTATE DEHYDROGENASE INHIBITORS | MERCK SERONO S.A. (CH) | 2012-02-02 | — | — | US | disclosed |
| CN-1946675-B | Separation of amine from a phenolic compound | DU PONT | 2011-06-15 | — | — | CN | disclosed |
| CN-1946675-A | Separation of amine from a phenolic compound | DU PONT (US) | 2007-04-11 | — | — | CN | disclosed |
| US-4418209-A | ANTIULCER, ANTIARRYTHMIC, ANTIDIARRHEAL, ANTISPASMODIC, ANTIPARASITIC, AND ANTISECRETORY AGENTS | WILLIAM H. RORER, INC. (US) | 1983-11-29 | — | — | US | disclosed |
| US-4326075-A | ANTIDIARRHEA AGENTS | WILLIAM H. RORER, INC. (US) | 1982-04-20 | — | — | US | disclosed |
| US-4203920-A | ANTIDIARRHEAL | WILLIAM H. RORER, INC. (US) | 1980-05-20 | — | — | US | disclosed |
| US-4147804-A | ANTIARRHYTHMIA AGENTS | WILLIAM H. RORER, INC. (US) | 1979-04-03 | — | — | US | disclosed |
| US-4060635-A | Amidinoureas for treating diarrhea | WILLIAM H. RORER, INC. (US) | 1977-11-29 | — | — | US | disclosed |