SCHEMBL1021333

SCHEMBL1021333

Cc1cc(Br)sc1C=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8234128 0.86
SCHEMBL8200634 0.86 RAB9A (0.42)
SCHEMBL5367283 0.81
SCHEMBL10016152 0.77
SCHEMBL12990402 0.77 PRKDC (0.46)
SCHEMBL12215859 0.76 PIK3CD (0.41)
SCHEMBL4442166 0.74 ERN1 (0.39)
SCHEMBL12025003 0.74 PDPK1 (0.32)
SCHEMBL25316693 0.73
SCHEMBL12917968 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 140 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260049073-A1 SPECTACLE LENS COMPRISING AN ORGANIC DYE OAKLEY, INC. (US) 2026-02-19 US disclosed
US-12552757-B2 NRF2-activating compound SENJU PHARMACEUTICAL CO., LTD. (JP) 2026-02-17 US disclosed
US-12532662-B2 Organic semiconducting compounds Raynergy Tek Incorporation (TW) 2026-01-20 US disclosed
US-12454525-B2 IL4I1 inhibitors and methods of use MERCK SHARP & DOHME LLC (US) 2025-10-28 US disclosed
EP-4573092-A1 2,3,4,9-TETRAHYDRO-1H-PYRIDO[3,4-B]INDOLE DERIVATIVES AS ESTROGEN RECEPTOR MODULATORS FOR THE TREATMENT OF CANCER Olema Pharmaceuticals, Inc. (US) 2025-06-25 EP disclosed
CN-115836054-B IL4I1 inhibitors and methods of use 默沙东有限责任公司 2024-12-10 CN disclosed
US-20240132519-A1 NRF2-ACTIVATING COMPOUND SENJU PHARMACEUTICAL CO., LTD. (JP) 2024-04-25 US disclosed
WO-2024039860-A1 2,3,4,9-TETRAHYDRO-1H-PYRIDO[3,4-B]INDOLE DERIVATIVES AS ESTROGEN RECEPTOR MODULATORS FOR THE TREATMENT OF CANCER OLEMA PHARMACEUTICALS, INC. (US) 2024-02-22 WO disclosed
EP-4273145-A1 NRF2-ACTIVATING COMPOUND Senju Pharmaceutical Co., Ltd. (JP) 2023-11-08 EP disclosed
CN-112352328-B Organic semiconductor compound 天光材料科技股份有限公司 2023-09-22 CN disclosed
US-20030096737-A1 Caspase inhibitors and uses thereof VERTEX PHARMACEUTICALS INCORPORATED 2003-05-22 US disclosed
WO-2002092590-A1 FURAN AND THIOPHENE DERIVATIVES THAT ACTIVATE HUMAN PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS GLAXO GROUP LIMITED (GB) 2002-11-21 WO disclosed
WO-2002085899-A1 HETEROCYCLYLDICARBAMIDES AS CASPASE INHIBITORS VERTEX PHARMACEUTICALS INCORPORATED (US) 2002-10-31 WO disclosed
US-5430059-A Treating heart disease EISAI CO., LTD. (JP) 1995-07-04 US disclosed
EP-0633248-A1 Butenoic acid derivatives Eisai Co., Ltd. (JP) 1995-01-11 EP disclosed
EP-0589491-A1 Butenoic acid derivatives Eisai Co., Ltd. (JP) 1994-03-30 EP disclosed
US-5292770-A Butenoic acid derivatives EISAI CO., LTD. (JP) 1994-03-08 US disclosed
US-5166188-A Cardiovascular disorders, antiischemic agents EISAI CO., LTD. (JP) 1992-11-24 US disclosed
US-4996227-A Administering nontoxic antitumor agents UNIVERSITY OF CINCINNATI (US) 1991-02-26 US disclosed
EP-0399358-A2 Butenoic acid derivatives Eisai Co., Ltd. (JP) 1990-11-28 EP disclosed