Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12166384 | 0.89 | RORC (0.41) | RORCALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL1830040 | 0.89 | RORC (0.41) | RORCALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL12166536 | 0.88 | RORC (0.41) | RORC | |
| SCHEMBL12166533 | 0.82 | ELANE (0.38) | ALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL21430555 | 0.78 | F10 (0.38) | RORCALDH1A1F10 | |
| SCHEMBL17294854 | 0.78 | RORC (0.42) | RORCGRIN2B | |
| SCHEMBL17294853 | 0.78 | RORC (0.42) | RORCGRIN2B | |
| SCHEMBL20584659 | 0.78 | RORC (0.42) | RORCGRIN2B | |
| SCHEMBL12166405 | 0.78 | RORC (0.42) | RORCGRIN2B | |
| SCHEMBL20446551 | 0.78 | RORC (0.42) | RORCGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2086995-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2012-02-22 | — | — | EP | disclosed |